Traveling with Type 1: Best way to keep insulin cool on long trips?

I'll also vouch for the Frio's, but I would caveat their use. You need to still keep the pouch out of the scorching sun and not place it in very high heat conditions like a closed up car in the sun. And they don't work well in very humid conditions, once the relative humidity gets really high > 80-90%, then evaporation stops and the Frio stops working. I would also caution you about hotel fridges, they often have terrible temperature control and you need to be careful they don't freeze your insulin.

I took a 16 day trip through Spain and Italy and had some days where the temperature was 100 deg and my Humalog in the Frio did fine. I also did a two week cruise and trip to mexico and my R/NPH did fine in the Frio outside, but that trip also had a twist.