I haven’t used the 2020 and the 722, but I just switched from the Animas 1250 to the MiniMed 522. Resevoir size is not an issue for me either, but I figured I had a few cents to throw at this conversation. All in all, both are very good pumps.
I originally went with Animas because of the waterproofing and the on board food DB. I found that my BGs went low too often when I swam, so I stopped wearing it in the water anyway. IMO, the food DB feature has great potential, but the entries are too cryptic to be of any real use. I hacked the DB and made it usable, but it’s too difficult to maintain that way.
The big thing I miss about my Animas pump is the way it’s bolus wizzard calculates a bolus in a low BG situation with insulin on board. Animas figures you got into this condition by accident and subtracts the IOB from the insulin recomendation. MiniMed figures you’ve still got carbs digesting and doesn’t subtract it. I typically get into this situation by a miscalculation or unexpected burning of BG, so Animas fit right into what I needed. With MiniMed, I have to find the Active Insulin line on my status and subtract it out from the calculation. Kind of a pain.
Yes, Animas gives you an extra digit setting basal rates (3 decimal places) and boluses (2 decimal places) versus MiniMed (2 decimal places for basals and 1 for boluses), but I have not found that to be much of a disadvantage moving to the MiniMed.
I do have one beef with Animas and that is that my pump broke 3 times in the 2 years I used it. Yes, they replaced it by the next business day, but the switch over is a pain. Also, two of those three breakages happened on a weekend so I was back to injecting for 2 days. Bummer, but there are worse things. I see a lot of these comments out there, so I don’t think it’s just me having problems with Animas pumps needing to be replaced.
On the whole, IMO, MiniMed is marginally more straight forward for me overall, but I don’t think you’ll be disapointed with Animas either. My recomendation is the 722, but it’s up to you.