It’s an interesting observation and worth knowing about. The explosive decompression information is something I hope no never utilize.
On the other hand, they’re seeing just how bad things can get (sea level airport, completely full cartridge, presumably the FAA limit of internal cabin pressure at 8000’). What do typical numbers look like?
I never even half fill a cartridge, so I’m probably looking at only 1/3 of the effect or less. In my experience I need more insulin when I’m on an airplane (probably because of the lack of activity). So the shortfall in delivery when I get off matters, but I’ve never noticed it in comparison to several hours of enforced inactivity followed by suddenly walking again.