Hydrogen Water for Diabetic Complications

Water enriched with hydrogen, which can be generated by dropping hydrogenating tablets into ordinary water or by pouring ordinary water into a special electrified tube, has been claimed by some researchers to play a role in delaying the onset of both type 1 and type 2 diabetes, and has also been said to help in reducing blood sugar, either when injected subcutaneously or drunk as a fluid. More interesting is the possibility that, by reducing the reactive oxygen species which are involved in the production of diabetic complications, it may also slow the development of complications. For example:

"Med Gas Res. 2012 Jul 9;2(1):18. doi: 10.1186/2045-9912-2-18.

Hydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney.

Katakura M#1, Hashimoto M#1, Tanabe Y1, Shido O1.

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Reactive oxygen species (ROS) production induced by α,β-dicarbonyl compounds and advanced glycation end products causes renal dysfunction in patients with type 2 diabetes and metabolic syndrome. Hydrogen-rich water (HRW) increases the H2 level in blood and tissues, thus reducing oxidative stress in animals as well as humans. In this study, we investigated the effects of HRW on glucose- and α,β-dicarbonyl compound-induced ROS generation in vitro and in vivo.


Kidney homogenates from Wistar rats were incubated in vitro with glucose and α,β-dicarbonyl compounds containing HRW, following which ROS levels were measured. In vivo animal models of metabolic syndrome, SHR.Cg-Leprcp/NDmcr rats, were treated with HRW for 16 weeks, following which renal ROS production and plasma and renal α,β-dicarbonyl compound levels were measured by liquid chromatograph mass spectrometer.


HRW inhibited glucose- and α,β-dicarbonyl compound-induced ROS production in kidney homogenates from Wistar rats in vitro. Furthermore, SHR.Cg-Leprcp/NDmcr rats treated with HRW showed a 34% decrease in ROS production. Moreover, their renal glyoxal, methylglyoxal, and 3-deoxyglucosone levels decreased by 81%, 77%, and 60%, respectively. Positive correlations were found between renal ROS levels and renal glyoxal (r = 0.659, p = 0.008) and methylglyoxal (r = 0.782, p = 0.001) levels.


These results indicate that HRW inhibits the production of α,β-dicarbonyl compounds and ROS in the kidneys of SHR.Cg-Leprcp/NDmcr rats. Therefore, it has therapeutic potential for renal dysfunction in patient with type 2 diabetes and metabolic syndrome."

Although the work with hydrogen water is still experimental, that is, it has generally been done only in mice and rats, if you are diabetic today it is worth considering whether you want to use it for added protection. A priori, water with additional hydrogen in it should not be harmful. You can buy a hydrogen water generating tube for about $80, and they are easily acquired because they have attained a certain cache among health enthusiasts.

Rolling eyes…