I am back to where I was last year around this time

You need to think about how quickly or slowly the insulin acts. If your pancreas is making insulin, it will be releasing it directly into the bloodstream, where it can act immediately. When you inject insulin, it sits around in the subcutaneous tissue near the injection site and is gradually absorbed into the bloodstream. Basal (long acting) insulins like Lantus are designed to take around 24 hours to be completely absorbed - so one injection per day will cover. Bolus (rapid acting) insulins lke Novorapid or Humalog are designed to be completely absorbed in about 5 hours. They are designed to match the speed of digestion of food. the Therefore 10 Units of Lantus will take much longer to bring down your levels than 10 units of Humalog.but it will do so eventually.

To add to the information about the use of the C-peptide assay: C-peptide is a by-product of the normal production of insulin by the pancreas - it is not present in injected insulin (which is manufactured in genetically engineered bacteria or yeast). Assays to measure insulin levels in anyone taking insulin by injection will not distinguish between injected insulin and insulin still being made in the pancreas. C-peptide can only have come from the pancreas, therefore it is a good measure of insulin production.

Joel

However, it’s important to remember that—like everything else concerning diabetes—there is wide variation even in this. Not all rapid acting insulins behave the same. Apidra has a significantly shorter cycle, for most users. And a given insulin will perform differently in different individuals. There is no substitute for empirical data. You need to determine how the insulin you use affects you.

True! But given the OP’s sketchy knowledge about the differences between long- and short-acting insulins, discussing the finer details would probably have been TMI.

Sure. Just putting it on the record for future reference.