Depends. I had a toughened, leathery texture on my skin from years of using cannulas. It was hard to pierce the skin during set changes. That all cleared up after more than a year of using Sure-T’s.
I have the same infusion site change spikes, and I handle them by always changing site before a meal. I change my infusion set, then I double my basal for 1 hour and bolus 1 unit, then I “wait for the bend” on my CGM. When the insulin starts to kick in (this can take 30-60 minutes), I bolus for the meal and start eating without waiting because I´ve already pre-bolused. Sometimes the bend seems like it´s never going to come, so I up the basal even more or bolus an extra 0.5-1.0 unit. It takes time, but it never fails. After this initial waiting and extra insulin, the site is always good to go for the next 2-3 days.
It’s been many years, but IIRC, I used to bolus about 2U or a bit less at set changes due to high bg’s after changing cannula sets. I don’t need to do that with Sure-T’s.