starting year 56 one week ago
Ray
You notice they mention that “both classes of therapies have been used in 1000s of new-onset cases, but never together,” which indicates that they are talking about a treatment applicable only to new-onset cases, before the beta cells have been completely burned out and have lost all capacity for regeneration. So if you’re not newly diagnosed, forget about a cure.
Also, any treatment which uses immunosuppressive drugs such as Cyclosporine, Mycophenolate Mofetil, or Tacrolimus is more toxic to the body than uncontrolled diabetes, so it is just paradoxical to apply these terrible poisons to cure a much more manageable poison like hyperglycemia. Most people don’t realize that if you take drugs like this for more than a decade, your chance of solid-organ cancer rises to 30%, and your risk of skin cancer is multiplied by a thousand. Which would you rather have, a cancer risk like that or diabetes?
Finally, all efforts so far to coax burned out beta cells back into operation have produced utterly feeble results which allow the newspapers to start shouting ‘cure’ from the rooftops but which are so small that they have no clinical significance whatsoever. The human immune system is very strong, and the reason we can survive serious infections is that our immunity usually totally destroys what it attacks so it never comes back. The same is true when the immune system goes haywire and turns on its own beta cells. We find this in transplant patients, who can get hypertrophied gums from the drugs they have to take. But this doesn’t happen in patients with severely receded gums, since seriously injured tissues just don’t grow.
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