@Brian_BSC, Thank you Brian. No my dissertation is not on the etiology of type 2 diabetes. I actually doing a study using avatar-based technology (cartoons) with the objective of increasing access to diabetes self-management education to those who don’t have access to it. Particularly those of low socioeconomic status. The education is basic at best, however, basic is better than nothing.
Respectfully, without discussing which research is more authoritative (I think all are doing their best to add to the evidence base) I was attempting (it seems unsucessfully) to draw attention to the context of the original poster’s comment pertaining to the mediators of type 2 diabetes. It’s not only at the pancreas, as your post and personal experience, rightfully highlight.
I was attempting to emphasize that diabetes is mediated by organs other than the pancreas as your post also highlights. I believe the individual, @rgcainmd was quoting would find (if s/he doesn’t already know) that type 2 diabetes is mediated at organs other than the pancreas.
Unfortunately, that is a common perspective.
My focus was on this part:
"Type IIs don’t have enough effect from their insulin due to resistance or eventual beta cell destruction to get their fasting blood sugar down to a good level.
True, but only partially.
This is why it is so important for PWDs who are prescribed the various classes of medication understand what organ system the prescribed medication is working on.
Thank you so very much or the reference to DeFronzo and on “set point.” I’ll be sure to read it (after my dissertation hearing).
And thanks for the suggestion on editing.