FDA Review Criticizes Avandia and GlaxoSmithKline

"Patients who take Avandia… are far more likely to suffer and die from heart problems than those who take Actos, a similar pill made by Takeda, according to FDA reviewers.

Avandia is particularly dangerous to patients who also take insulin. By contrast, Actos can be taken safely with insulin, according to the review."

More details:
http://www.nytimes.com/2007/07/26/health/26cnd-avandia.html (NYTimes)
http://society.guardian.co.uk/health/story/0,2135982,00.html (Guardian Unlimited)