OK, I was bored and playing on the internet. Found some neat info, at least to me!! LOL
An important clinical sign differentiating T1DM from T2DM is insulin deficiency, which most often presents with ketonuria and/or ketoacidosis.
The Immunology of Diabetes Society has defined LADA as follows: 1) age over 30; 2) positive for at least one of the four antibodies commonly found in T1DM (ICA, IAA, IA-2, and GAD-65); and 3) not requiring treatment with insulin within the first 6 months after diagnosis.
Ketosis-prone T2DM is characterized by an acute presentation of ketoacidosis, a strong family history of T2DM, negative autoantibodies, and an intermediate insulin response to meals. In addition, these patients do not require long-term insulin administration to maintain glycemic control. Once euglycemia is achieved with insulin at the initial event, patients can be switched to oral hypoglycemics. Other researchers have labeled this subtype “Flatbush diabetes”, Idiopathic type-1 diabetes, and type 1-b diabetes. These patients are usually obese, African-American or Hispanic, with negative genetic and autoantibody markers. Although these patients may be managed with oral hypoglycemics for some time, they progress to insulin requirement more rapidly than patients with T2DM.
So there it is type 1-a, type 2, LADA and Ketosis-prone T2DM / type 1-b. See I learned something!! LOL
