Brian - why would you keep saying something which is just wrong? Did you not read the label I posted above?
Now, why would a T2 who still has some beta cell functionality left take a basal? Historically its fear of hypos and to limit the PWDs hypo risk. Before afrezza, insulin was just too damn slow. With afrezza as long as you are not taking a basal you have very little chance of a hypo. As Al Mann said, you really have to try.
T2s first lose post-meal first phase insulin release. The way to treat that is to blunt the spike before its goes 140+. To do that you need an insulin which works like the pancreas and there is only one.
Now why does it work like the pancreas? Two reasons; the delivery methods gets it into the blood immediately like taking it IV or through the pancreatic canal; the second is because it was stabilized as a monomer so speed of action is very consistent.
Now as far as cost, its way too expensive. I would like to see a 90 cartridge box being sold OTC for $29.95. Maybe if more people started understanding what afrezza is and what it can do, more people will start demanding it and more insurance companies will cover it. Once the insurance companies start understanding that in the long run it will be a huge money saver for them they will all cover it.
But if people keep saying things like it must be taken with a basal and keep insisting with authority they are right the average PWD won’t know the truth and will never even ask about it. It will go to the dump heap just like BP would like and never become the paradigm shifting treatment Al Mann envisioned.
Do you realized Al Mann in his studies actually showed T2 beta cell improvement? Now that DeFronzo is showing the same with his TZD/GLP-1 cocktail we have to different approaches achieving the same result both by keeping non-diabetic TIR. The key in stopping T2 progression is non-diabetic TIR.
Now would you rather take the human insulin with minimal chance of hypo or the Actos/Byetta cocktail? Additionally, afrezza is NOT a subq RAA. Its human insulin which is delivered almost immediately into the blood. When the AACE finally catches up in a few years they will get it right and it will be in its own category. Right now the AACE document needs a clean-up. How long did it take the FDA to get the speed right on the afrezza label, 3 years?, and that was a no-brainer.
Here is a video you may want to watch where Al Mann talks pros/cons of current insulins. Al was one of the great minds in diabetes. He invented the insulin pump; the CGM; first implantable pacemaker; solar panel; etc. He starts talking diabetes at 8:30m but it gets interesting at 11:00m and then talks about stopping T2 progression at 15:00M “interesting this lowers insulin resistance… this is even likely to slow and even stop the progression of Type 2 diabetes” www.youtube.com/watch?v=SvZxYmYPXYQ
Why does it seem you don’t want people to know about afrezza and what it can do? I know from personal experience it works and stops the progression. I also know from personal experience the dangers of the T2 orals and the deadly consequence some have had like Orinase. Do you think UpJohn did not know the dangers of Orinase? Why was Trulicty rushed to market? What was done, 5 small studies?