This was surprising. I focused much of my health thinking avoiding heart disease, and generally assumed, no matter how much effort I put in, I was still going to die of a heart attack. I still might, but I was surprised to see T1D risk was lower than that for T2D.
When analyzed by separate cardiovascular events, DM1 was associated with less myocardial infarction, percutaneous coronary intervention, stroke, and limb ischemia than DM2. Overall cardiovascular event probability was lower in DM1 than in DM2 across all 10-year age categories, in both female and male patients, before and during/after the coronavirus disease 2019 pandemic, and after adjustment for comorbidities, hemoglobin A1c, and serum creatinine.
Finally! After decades of lazy cardiology research lumping all diabetics together we have something that says we are different and we require a different cardiology standard of care from T2D. The data set contains ~150k T2D, 5.5k T1D which sounds convincing to me.
@Helmut No, they didn’t expand their analysis to non-diabetics. The data set only included people referred to cardiologists so it is biased to showing high rates of CV events.
@spdif, I was hoping to die from a heart attack instead of dementia. I am wondering whether this study implies that I need to eat more pepperoni pizza.
@Helmut - One of the problems of modern life and medicine, we are outliving our brains. We’ve reduced our deaths from cancer and heart disease, only to live longer and have our brains give out on us.
@Helmut - I did some basic AI search and found confounding results. initial results stated that T1D compared to T2D for death from heart disease was either same or higher. I then prompted it to explain divergence from the recent studies, and it came back the studies I mentioned, but sited other potential issues, like comorbidities and improved management tools. The summaries made sense.
That said, the study I mentioned result’s were “after adjustment for comorbidities, hemoglobin A1c, and serum creatinine.” It might be a little bit of a statistical illusion, since it is a little like saying, if you removed all the things related to increased risk of heart attack, diabetics are like normal people.
Regardless, as @spdif alluded to, part of their message was that T1D and T2D are fundamentally different and that those differences should be considered in treatment.
@JamesIgoe, thanks for your research. It’s not surprising that two diseases (T1D and T2D), caused by entirely different pathophysiological mechanisms, do not share the same risks. I am sure that someone will get a PhD for pointing that out.
Reminiscent of the early Covid news re: high risk for people with “diabetes”. Turned out to mean people with obesity and T2D. Not that there was no need for caution - just poor reporting.
