I read that: ‘metformin suppresses gluconeogenesis’. I’m on lchf diet (something like: 70-80g carbs, 80g protein and 110-130g fats). It means that on metformin if I eat for example 80g of carbs I’ll ‘absorb’ less carbs or my body will not use gluconeogenesis to ‘make’ extra sugar that needs? I’m just curious how it works
Metformin works in the stomach to prevent your body from absorbing sugar and suppresses glucagon output from the liver. I’m type 1 on low carb and I’ve been using metformin for about a week exactly for those two things because I had developed some sort of insulin resistance after a bad cold last year and so far it’s working great.
I’m Type 1 on a low-carb diet and have been using metformin for about a year, I think. I didn’t feel like it was making a huge difference so tried to stop it, and wow, my blood sugar shot up to 18-20 mmol/L and stayed there for two days. So clearly it is doing something to benefit me and I will keep taking it.
Here’s how metformin works: