I can tell you that I used R-Alpha Lipoic Acid for my neuropathy. It was actually beneficial for all of my complications. After diagnosis and beginning insulin the pain and mobility were horrible, beyond words. I started out with 200 units of R-Alpha Lipoic Acid and gradually worked my way up to 600 units morning and 600 units in the evening. I did this for about three years.
This supplement made a noticeable difference almost immediately. I was encouraged to use it by all of my doctors even though they had not told me about it. I found it and began using it on my own.
I also take a vitamin B complex which has been helpful as well in my healing. I looked into evening Primrose oil and did not choose to use it. All I used was the R-Alpha Lipoic Acid and basic vitamins along with tight control. My pain and dexterity issues are about 5% of what they were in the beginning.