Thanks for this info my endo thinks the same I just recently started injecting into my bottom for the summer because I get bruises on my thighs so Iām back to my thighs endo says Lantus only in arms thighs or abdomen I swore my CDE 2 years ago said that was okay for injections. You were right I was high the next day combo of used up insulin and glucose tablet storm from 10pm. Robin
Thanks for responding, My endo thinks that is what happened because it felt SO different from just being low I could feel the trend or crash just so fast. I have changed injection sites back to thighs this particular injection was in my bum cheek ( canāt believe I just typed that) well Never again. Robin
Here are three sites that discuss Lantus Lows:
http://www.healthcentral.com/diabetes/c/5068/11388/lantus-lows/
http://dapaice.com/potpourri.pdf (scroll down to the graph near the bottom)
http://www.diabetesmonitor.com/thcn-lantus-continued.htm
This happened to me when I was taking injections.
I suppose itās possible, but color me skeptical. I think itās more likely you just had a freak low, perhaps from eating too little or exercising too much or shooting up too much at dinner. These things happen, often for no discernible reason (though Iām sure youāre body knows; unfortunately, your body is not a great linguist). Iāve taken long acting insulin for about 13 or 14 years, and Iāve hit blood vessels, but Iāve never had an instant low because of the long acting.
The way Lantus works is that itās soluble in acid and precipitates at the pH of interstitial fluid. Perhaps for some reason your interstitial fluid was more acid than usual, or perhaps the Lantus you got contained more acid than usual. But if this happened every time, bottle after bottle, the latter isnāt likely.
Other long-acting insulins wouldnāt have the effect Lantus does when it goes into a blood vessel because theyāre slowed down by different means.
Iām a type 2, and wasnāt taking bolus insulin. I injected Lantus when I got up in the morning. If I went down 100 points Iād be dead because thatās where I started.
Robin,
Iāve had this happen twice. Iām type 1.5 and I only use Lantus (8u in the AM). Each time I had a fasting around 120 and after my injection dropped to the 20s within 15 minutes. Scary. I, like you, was frantically eating whatever I could get my hands on. I have to think that I somehow injected into my bloodstream; otherwise, I cannot explain such a quick reaction/low. Or, perhaps I could just blame it on the unpredictability of diabetes : )
Thank you for your insight, I do think I was dehydrated that evening and also had just recently moved that injection from front of thigh to buttocks, and the Lantus insert says arms,abdomen or thighs oops well Iāll never do that again! Robin
Thank you I love this Tudiabetes because I donāt feel all alone with this. For the last month I make sure Iām at 180 for bedtime and this Lantus injection, you do not need insulin with meals that is great! I hope that is all you need in the future when my pancreas quit it just quit:( Robin
This can happen with Lantus. I call it āLantus lows.ā
Lantus lows - Insulin & Pumps - Diabetes
(Much of the original blogpost has been cut out.)
The way Lantus works so slowly is that itās acidic in the bottle, and when itās acidic, itās soluble (this is also why it stings). When you inject into the body, the bodyās pH neutralizes the acid and it becomes insoluble and clumps. The clumps dissolve slowly.
But if you inject into the bloodstream, or close to a capillary, it gets carried off and wonāt clump. It then acts just like R. If you normally used something like 5 U of R but you use 20 U of Lantus, you can see why youād suddenly go low. It happened to me once.
A friend says with him it takes about 45 minutes, so your 30 minutes isnāt far off.
Agreed. itās really hard to get low on Lantus. Especially after 30 min 