In the end people just have to find what tools/medications work best for them. While this inhaled insulin wouldn’t be something I’d particularly be interested, I think its key we have access to safe and different tools to manage this.
You keep saying "it has taken the swings out of the picture for me" but then you say you take it before eating and if after 1 hour you are over 200 you take more, and many times you say you check and if it's high you lower it in minutes. It seems to me you are "following your BGs" instead of predicting them and avoiding highs.
Anyway I find interesting your experience, but I think this product would be very well suited for an artificial pancreas device.
An AP has a desperately need for a fast acting-short action insulin (and an accurate and robust CGM).
If only they could find a way to "spray" this insulin in the lungs through a device in a practical and confortable way ...
I would like to know if you own the stock. Thank you
Afrezza user, Thank you for posting this information, but could you answer one question please? Do you own Mannkind's stock? Thank you.
That was an example as a type one diabetic I doubt there is one person even on this board who never has a reading of a blood sugar of 200. I doubt there are any diabetics who can keep their blood sugar between 80 and 130 without ever going over that. So when I say it is high such as a reading of 150 I can correct it into the normal range in minutes. You make a great point about Predicting them. I been doing that for 10 years. You only need one prediction to be wrong and its all over. My only point is that this has changed my life and its working great for me. I am a person who does not want to wear devices attached to my body. I want to eat what I want to eat. I am very fit and active. I swim a mile at a time. I cant afford lingering insulin in my system. Not all products fit all patients. I am simply reaching out to people who have had low blood sugar problems and are looking for another solution. Most people do not follow a strict protocol as many here are following in their management of diabetes. The predicting of your blood sugar 4 hours from now after I eat and take Humolog and Novolog is not a simple process if you are a person who snacks often etc etc etc. I have many diabetic friends on the pump and they are having many problems with the lows. It is a big a problem as one in 20 diabetics will die from a low in their lifetime. I am sure I would of been part of that statistic. As mentioned many times I do not have that fear now as I really never worry about it. I am just a diabetic type 1 who has searched for a better mouse trap and I have founded it.
That sure would explain a lot, wouldn't it Equestrian?
I can't guess the logic on how a spray insulin in fixed doses can avoid lows and highs.
I keep my opinion.
Maybe, but I'm not sure it would be worth the time. MNKD is trading about 2.5 m shares per day. I seriously doubt our little community could effect the share price in any way, if thats what we're getting at.
I think people are just curious as to why the OP is pushing this product as some kind of panacea and then ignoring questions about very real concerns when they are posed. (Such as how anybody could maintain stable blood sugar with only two dose possibilities, both of which are larger than most type 1's use.)
To me, the dosage size seems like an "apples and oranges" thing. That doesn't bother me. I can also see that perhaps the large dosage is "made up for" by it not hitting as hard or something like that. I'd be intrigued to try it but I'd probably try it on something lower carb before I blazed away at donuts with it.
From the time I read the original post I felt that it did not pass the smell test. It sounds like advertisement to me. But I can be cynical sometimes so I have kept my mouth.
I hope I'm wrong.
All good points, though it seems to be the exact opposite of the 80/180/240 testing to today!
Your last paragraph makes sense and don't really understand why if one thing were possible the other wouldn't be!
AR, I understand that the numbers don't translate directly but I think the OP said it was like half so equivalent to 5 units and 10 units, still way more than many of us use! But it isn't just the size of the dose as the lack of options. After seeing the flexibility of the pump's precise doses vs whole units on MDI, it again, seems like going in the opposite direction.
Ditto. I just couldn't put my finger on it well enough to report it.
did anyone ever receive a response as to whether he owned stock?
NYSE said he can't say .... (smile)
I used Exubera and it worked a little faster but wasn't consistent.
I use a T-Slim pump now but if I have access to Afrezza I will try it. It would be nice to have an insulin absorb and be gone quickly. If I used that in conjuction with a pumped basal I could avoid more spikes and low night time blood sugars from insulin that waited too long to start working. Or who knows, maybe I would go back to injected basal ie lantus and use the Afrezza to bolus. If I watch my CGM I could inhale twice per meal ...
I'll try anything twice.....
I disagree with still youngat heart. I work hard to maintain control but I have highs and lows all the time. My brother had a low in his hot tub and drowned, died and was amazingly brought back to life. I fractured my shoulder during a night time seizure 6 months ago and yes basal may have contributed but its the fast acting that doesn't always kick in when it should and then works while sleeping and lowers too far. Why are you so against this idea?
Normal pancreas sends insulin to the portal vein. I saw that on a website somewhere...I therefor assume that insulin is normally delivered intravaneously which is why it works so quick and is then done. The problem with subcutaneous injections is the delay and inconsistency in start / stop times.
My point is that inhalation could result in fast start times comparable to injecting directly into a vein.
Well as much as Ive enjoyed being advertised to, I have this awesome insulin called Humalog. It injects right through this cool device called a pump. They have these neat sensors so I wont die from low sugar (thank you poster for your lovely scare tactic there though!) If I can't afford a CGM there are lots of nice organizations that will give me a dog. I monitor my eating. I haven't had a truly dangerous hypo in a very long time. REALLY! I have an insulin to carb ratio. I don't use slide and scale anymore which is what this insulin sounds like it is asking you to do. My blood sugar sits from 80-110 all the time. I rarely go high, I rarely go low. I am not perfect of course, no one is, but this product seems rather ill conceived and this doesn't seem like a proper forum to drum up business. Really, seriously, its a little condescending and rude IMHO.