I started to try Afrezza yesterday and it indeed is extremely fast-acting.
I have tried Fiasp, Humalog, Novalog in combination with Lantus and/or Toujeo. I have an unusual metabolism in that any of the injected insulins take an exceptionally long time (2 hours or more after injection) to begin to lower my blood sugar. My endocrinologist thought that I was crazy and that this was totally impossible when using Humalog, Novalog, or even Fiasp, but my Dexcom doesn’t lie. Luckily, I’ve run into several people on this Forum who have the same problem with their Type I that I do… exceptionally long time between injection and the lowering of blood sugar.
Afrezza, after three days of use seems to actually work within 15 minutes or so. However, it remains in my system for only a very short time. If I take 20 units (one 12 unit and one 8 unit), I can now eat 15 to 20 minutes after the inhalation and maintain a blood sugar level of below 135. With Fiasp, if I tried to eat the same meal (let’s say a Burger King Whopper) 20 minutes after injection, my blood sugar would be up at 300 within 20 minutes after eating the junk. Then, I’d experience hypoglycemia (50) 2 hours later…
Afrezza clears my system within 1 hour after inhalation. Thus, it acts fast, and clears fast. If I eat a slowly-digested meal with only protein and comple carbs, Afrezza clears before the food is completely digested and my blood sugar goes up into the high 100’s (170 to 220 or so). If I eat crap carbs (like that Whopper), then the Afrezza works just fine to keep my blood sugar between 100 and 140.
We’ll see how fast Afrezza keeps working over the next month or so…
I’m hoping that the company that makes Afrezza gets it only my ObamaCare’s approved drug list so I can continue using it.