I’m assuming the clog has occurred because the the Medtronic pump gives a “NO DELIVERY” error message meaning the pump can’t move the insulin for some reason. It could also result from kinked tubing etc., but since the error only occurs when using Apidra (and tubing is fine), I’m assuming the insulin is clogging in the infusion set or reservoir. There is nothing visible that would identify a clog.
As you point out, diagnosis is difficult and many factors could result in occasional high blood sugar and possibly even the No Delivery error - so I’ll keep trying.
I haven’t tried the MM continuous glucose monitor (CGM) yet with Apidra, so I’m trying that today with a new reservoir. The continuous monitoring should help correlate the time of high sugars with age of the Apidra.
By the way the last reservoir of Apidra worked flawlessly, but that’s only 1 of 4 reservoirs, but I’m hoping that continues.
Oh yes of course. I misread (or read too quickly) your previous statements as you received no “no delivery” charge. My mistake. I understand now.
With Caleb, my gut is usually 95% right that insulin isn’t getting through, particularly when I see his bg rising on CGM. I try to rationalize the twenty other things that could be causing it though. Fun times.
Hoping for 2 of 5!
Wow, I just finished reading this thread and its been very useful.
I’ve been using the MM pump (713 (4 yrs) / 723 (1 yr)) for over 5 years now with Humalog. The last problem I had where I spiked and took forever to come down, I was informed that most likely it was a clog. I am assuming the clog occurred in the cannula. The tubing looked fine, no kinks. When I pulled the infusion site, the cannula wasn’t bent and I thought I saw a small drop of blood in it. I had originally thought I hit some scar tissue and had a dead zone or that my bottle of insulin went bad.
On my last visit to my Endo, he gave me a bottle of Apidra to try out. It took me a bit to get the courage up to make the change but I finally did. Unfortunately when I got to about 60 hours (2 1/2 days), I began to spike! I had read in other places where people seem to see a 48 hour limit, just as stated in this thread.
I double check the insulin web sites for Apidra, Humalog, and Novolog. Apidra and Humalog say the entire set should be changed every 48 hours, where Novolog says the infusion site should be changed every 3 days and the reservoir every 6.
This 48 time limit is a little frustrating to me. I normally go 3 to 3 1/2 days with the Humalog.
However, I might be inclined to change my infusion set every 2 days if I get such steady graphs from my CGM like I saw. I am taking a small break, in order to kick a cold, then I will try to switch back to Apidra.
If anyone is interested, I had started an Apidra Users group here a week ago.
Brad, Too bad about your problem. I’ve used Apidra in my first MM 522 and now for the last 1 1/2 years the Omnipod. I have never experienced a clog. I’ve been using Apidra for 3 years now.
Hi everybody. I am new here - just signed up, but I was anonymously reading for some time 
Also as new in the forum, I am new to the pumping world. I have Minimed 715 + apidra for the last 11 days. My HCP has suggested novorapid, but it had terrible onset like 1.5 hours (during that time BG is already 18-20+) and more terrible tail of six hours… It just wasn’t my insulin… So she agreed that apidra which I’ve been using during the last 5 years and had no issues while were on pen would be better choice. There was a “but”… She told that apidra clogs more often the sets… Ok I said… But again the but… I’ve ran the first set for 2days with novorapid (and then changed back to apidra). Then my first apidra reservoir lasted on the sixth day (not full 6 days but almost). Nice… Next one clogged on day 2… Next one also on day two too (just half an hour ago)… And that frustrated me. Minimed’s sure-t set can be detached and I did it. Ran 1u bolus and voala - it passed the long tuning and appeared on the n top of the connectors needle… Reconnected - again no delivery message on the pump… Then I’ve removed the sets needle from body and ran another 1u… No drop on the needle top. After one more try for 1u the pump again complained no delivery. Tried delivering units, priming… The pump could not push any fluid though the needle (the body one)… I’ve taken the filling plunger (with the needle out of the body of course) and pushed - no result… Pushed harder and harder till it had unclogged… There are serious resistance…
So it was the needle in my case.
I’ll try the next time too to see which part is getting clogged…
I’ll keep you up n to date.