I would be interested to hear from anyone using Apidra in an insulin pump.
I’ve been using Novolog since I started on a Medtronic 722 (with CGMS) pump 3 years ago. I recently tried a switch to Apidra to help reduce postpandrial blood sugars. It has accomplished this…but I find it annoying that the pump seems to clog (NO DELIVERY msg) after only about 2 days with the Apidra insulin.
Novolog (NovoRapid) isn’t as fast acting, but doesn’t require as frequent infusion set changes (at least 5 days for me). I have never experienced a clog (or NO DELIVERY msg) with Novolog.
The Apidra product write-up from Sonofi-Aventis does indicate a 48 hour limit in any pump. I’m not sure if that is just a manufacturers CYA thing or if everyone sees this limit. Since clogs occur at unpredictable intervals - this doesn’t seem to be a vial insulin for pump users. i.e. if I’m sleeping, by the time I realize I have a clogged infusion set, my blood sugar is extremely high (normally I’m well controlled).
As mentioned, I use a MM 722 with the Quickset (43") infustion set. The clog is repeatable in that I’ve never completely used a 3.0ml reservoir without experiencing a NO DELIVERY message from the pump (have been using Apidra for a month now). When using Novolog, I was going 5-6 days (avg. 50 units/day) on a 3.0ml reservoir. With Apidra I am throwing out about 1/2 the reservoir every time due to the NO DELIVERY message as a result of the clogs.
I would be interested if there’s anything I could change to extend the life of Apidra in the pump…i.e. would a shorter infusion set help, would inserting the infusion set in a different location help? Also, once a clog has occurred, is there anyway to clear it (and avoid throwing out the infusion set).