I'm curious, however, why the authors excluded all mention of T1D.
I imagine for a couple of reasons Terry.
First, it's a review article and I think the authors are being very careful not to overstate the results of their literature review. Compared to the amount of literature reviewed, the short conclusion section really does seem subdued.
A second related issue, reading through the review and with just a cursory look through the citations, it seems as though the emphasis is on the effects of insulin on metabolic pathways and how that relationship seems to be somehow broken in the list of condition addressed. T1 isn't necessary a problem with insulin usage as much as it as a problem with insulin production.
As long as T1s have access to exogenous issues, we can still use it effectivley, perhaps, ameliorating some of the impact of these conditions.
Definitely and interesting read.