Dave,
I don't think you'll be able to leave your pump behind unless you have some other way to handle basal. I'm not all that familiar with pumping as a T2 but don't you need that little trickle...
If you can get away with only Afrezza I'll be very envious.
Maurie
Thanks Dave, I’m kind of a type weirdo right now. My hyperglycemia is not chronic, strictly post meal. My endo thinks early onset T1 (honeymooning?) but we haven’t gone to insulin yet despite high post prandials because my a1c is still good and my fastings are good. I can control with a strict low carb diet but because I lost a lot of weight (and because I’ve been gluten free for 18yrs) I honestly would like to be able to eat moderate carbs, gain back my weight, maybe have more energy and not have such a restrictive diet. That’s why I’m very interested in the afrezza. We measured my insulin during my OGTT and I don’t have the 1st phase spike and my output remained sluggish throughout the test. I had some success with prandin which forced my pancreas to produce more insulin and stopped the spikes but I had side effects I didn’t like, so…for me a super fast acting insulin might be good. I wouldn’t use it with very meal and I wouldn’t go crazy with the carbs but maybe I’d gain back some weight and feel better?
Hi Lilli. If it were me, I wouldn't wait for Afrezza--there isn't enough known about it right now. I'd try some fast-acting insulin, very conservatively at first, and see how that works. well, that's just me!
I hear you Trudy. I see my endo again this fall and plan to see if he’ll try either afrezza or injections, I’m open to either. It seems he’s just waiting for my BG to get worse before he’ll let me try insulin. So far he keeps giving me different orals for the high post prandials. I’m going to have to use the prandin again until then or go super low carb. Or yes, find another doctor, but truthfully I’m not sure where to go for help at this point.
While I'm very interested in Afrezza, I agree with Trudy. Injected insulin can be highly effective with your post-prandial spikes. You wouldn't have to use much so the risk of hypos is less. You can use it now and try Afrezza when it comes out.
Your residual pancreatic function is a big bonus. Giving it a little insulin help may lead to a longer honeymoon.
Accidentally deleted my previous reply which Terry and Lili were replying on, sorry
I’ve read that too Terry, that some docs think a little insulin in the early days may extend the honeymoon. I also know that some docs think meds like prandin may exhaust the beta cells sooner, not good. I do feel lucky to still have my own background insulin and I’d like hang on to that for as long as I can. I’m as a surprised as anyone that you can have symptoms and almost 100 documented post prandials over 200 (meter, lab & CGM) and still not be put on bolus insulin. But my A1c is good so the roller coaster doesn’t seem to matter.
I called them was told they are looking for a partner to make a commercially available product and it will be at least six months to begin availability.
Oh thanks for the update Aaron, I guess I’ll have to stick to prandin or try to get apridra if I want better post meal control before then…
Hey everyone... Mannkind has a really really good video on their site explaining insulin response to food, and how the timing of endogenous, and various injected insulin action curves differ.
This video is not a direct sales pitch for Affreza, being pretty much a solid piece of scientific information. Of course, the timing question on administration, time to peak, time to zero IOB are all facts that make the case for Afrezza naturally :-)
Here's the video: Diabetes: "Timing is Everything"
That’s a good basic video even for simply explaining the whole BG cycle, I’ve always been a bit confused about the livers role and it helps to visualize the process, thanks for sharing it!