FDA Approval of Afrezza inhaled quick -acting insulin

Type 1 and LADA
#1

I had an appointment with my endocrinologist who told me that if I ever got tired of using an insulin pump, I could use the new inhaled human insulin(it is actually powder) that is ingested orally by Unit. I looked it up for the manufacturer ManKind and all the prescribing data is there.

I wonder if anyone has started using it for Type 1. You must also use a long-lasting insulin like Lantis, injected once or twice a day.

It sounds promising and I just wondered what people had experienced so far, since it is new.
Is it possible to bolus for a meal and then take more if you decide to eat more an hour later or before your next meal?

How does it affect the throat? One side effect listed was a cough or throat roughness.

thanks, if anyone has already tried this.

#2

here are some discussions we've had on Afrezza, please add to them if you'd like to get more opinions

https://forum.tudiabetes.org/topics/fda-afrezza-press-release
https://forum.tudiabetes.org/topics/afrezza-an-ultra-rapid-acting-insulin-inhaled-insulin-onset-12
https://forum.tudiabetes.org/topics/what-if-you-could-get-insulin-without-needles

#3

The FDA just approved ultra-rapid acting Afrezza, an inhalable insulin, about one month ago. It is not commercially available yet. The business press speculates that MannKind will have to find a deep-pockets partner to bring this product to market.

I am very interested in this product but am concerned about respiratory side-effects. This insulin starts to act immediately and peaks in 12-15 minutes, very impressive numbers

#4

Yes, and if that 12-15 minutes holds reliably, it truly becomes a "mealtime" insulin that can be administered when you eat. Tremendous added flexibility.

With current fast analogs, I have to pre-bolus 30-45 minutes to achieve near-normal control. Otherwise, I get a big spike that eventually comes back down. Pre-bolusing I can usually stay under 140-150 postprandial. Eat the same meal but dose right before eating, and I'm headed to 200-220 at the peak.

#5

I already have pulmonary nodules so I will just say no