My brother consistently has >250 glucose after a set change. He swears he fills the cannula correctly and he doesn’t see bubbles in the tubing. Any ideas why this happens??
It would be extremely helpful if you told us which pump your brother uses.
This is a quite common experience, with a plethora of possible reasons and resolutions.
My sets require 0.3 units of insulin to fill, but my trainer told me to use the 0.7 unit option, because supposedly the flesh needs saturated with insulin before it actually starts to absorb. I’ve long since realized that the tiny over-delivery she recommended is NOWHERE CLOSE to what I actually need. I give myself 2 full extra units now, via the load menu on my T:slim so it doesn’t register as insulin on board.
Basically, the first 2 units at any new site are useless to me. If I don’t pre-emptively “waste” them into my flesh, then it’s going to waste those 2 units out of my basal delivery instead, driving me high.
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Kind of the same thing 
@Robyn_H is saying…
It’s helpful to do an “activation” bolus. Whenever you do a change, a small bolus gets the site going.
I leave my old set in for a few hours after I change.
I notice if I take it out right away, it will leak out insulin.
My spike doesn’t hit as hard as his but maybe I’ll spike up 20-30 mg/dL.
Still keeping the old one for an hour eliminates the issue.
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