Sanofi And CureDM to
Develop Diabetes TreatmentDrug Discovery & Development
- April 09, 2010
NEW YORK (AP) -
Sanofi-Aventis and CureDM Group Holdings LLC will work to develop a diabetes treatment aimed at restoring a patient's ability to produce
insulin and other pancreatic hormones.
The deal is potentially worth more than $335 million to biotechnology company
Current diabetes treatments focus on either adding insulin into the body or
helping diabetes patients better regulate the insulin their bodies already make.
The drug candidate, called Pancreate, has been shown in preclinical studies to stimulate the growth of new insulin producing islets in the pancreas. That
results in restoring a patient's normal metabolic function and glucose control
in the blood.
Preclinical trials involve laboratory work and often include laboratory
The company plans to start Phase I studies, which involve human subjects, later this year.
Under the deal, Sanofi-Aventis is granted an exclusive worldwide license to
develop, make, and sell Pancreate and related compounds. CureDM will receive an
upfront payment, along with development, regulatory and commercial milestone
payments. Overall, those payments could total $335 million.
Also, CureDM is eligible to receive tiered royalties on worldwide product
Date: April 8, 2010
Source: Associated Press