Sounds scary. I’ve seen a few negative posts on the side effects of Invokana. Seems like a drug you’d only want to use if nothing else was working.
Looks like the likelihood of amputation doubles:
"The CANVAS trial showed that over a year’s time, the risk of amputation for patients in the trial were equivalent to:
5.9 out of every 1,000 patients treated with canagliflozin
2.8 out of every 1,000 patients treated with placebo
The CANVAS-R trial showed that over a year’s time, the risk of amputation for patients in the trial were equivalent to:
7.5 out of every 1,000 patients treated with canagliflozin
4.2 out of every 1,000 patients treated with placebo"
The article is on the FDA website. I’d call it pretty legit since it’s referencing specific studies and direct conclusions.
Here’s a thread that discusses this problem: Invokana Amputation