Saw this on diabetesmine and wanted to share. I dont know much about this therapy but just a little bit of reading it certainly looks interesting!
We’re making big strides towards a band-aid sized device implanted under the skin of people with diabetes that would release insulin as needed, potentially eliminating the need to check blood sugars, count carbs and dose for insulin through injections or a pump!
Yes, on Friday news broke that San Diego-based biotech company ViaCyte filed an Investigational New Drug (IND) application with the FDA to move forward with Phase I/II clinical trials in people with type 1 diabetes. The trial would evaluate the safety and efficacy of a new stem cell-derived encapsulated cell replacement therapy, known officially as VC-O1. Basically, that product uses pancreas endoderm cells derived from embryonic stem cells and would be put into the body using something called the Encaptra delivery system.
You may remember from our past coverage that Encaptra is a flat device about the width of a credit card. It would be implanted in under the skin (possibly in the upper back) through a simple outpatient surgical procedure and designed to last at least a year, possibly up to five years, before it would need to be replaced.
This device would be loaded with insulin-producing cells before implantation, and contains pores that allow glucose and insulin to be transferred through, but not antibodies — meaning insulin would be released as needed in response to the varying glucose levels, but no immuno-suppression drugs will be necessary because the device is protected from autoimmune attack by the sheet’s membrane. Very cool!
More on the original article: http://www.diabetesmine.com/2014/07/newsflash-band-aid-sized-encapsulation-device-implanted-in-first-person.html