I've only had the pump for about six weeks now, but I travel about 30-40% for work, so I asked some detailed questions of my Medtronic support team about this, and then clarified with the TSA folks at Pre-Check.
Medtronic does not want you to go through the full-body scanner (where you raise your hands over your head and stand still while it goes around you), and they recommend that you not send the pump through the x-ray scanner for carry-on bags. Instead, they suggest that you leave the pump on you, and walk through the metal detectors.
In practice, I asked a couple of TSA agents about it, and have found that if I just point to it and say that I've got an insulin pump, they'll just wave you on through the metal detectors. Now, I know that the Pre-check metal detectors are a little less sensitive than others, but I have yet to set off the metal detectors when I walk through, and have not had a TSA agent even express concern about my pump.
I've only been on a few trips since I got my pump, but I will let you know if anything changes going forward.