[This was posted at 8:30 Thursday morning on the Lantus/Humalog Users' Forum but has received zero response; re-posting here with the hope someone will answer.]
I did a single shot of Lantus at night for about a year, recently switching to split doses to alleviate highs after lunch and morning lows. Been futzing around with proportions and timing for four or five weeks to correct bad crashes overnight and after breakfast, and a few lows in the evening. The single shot dose was 19u, so I began with an even split at 12-hour intervals. Now the split is 60/40, 12u AM/9u PM -- the interval is still approximately 12 hours. The overnight and after-breakfast lows have decreased for the most part, but I now question the wisdom of the timing.
Given a morning dose that is 25 percent higher than the evening's, is it reasonable to conclude that the morning shot should be given earlier?
(Does anyone else out there waste brain cells on such questions?)