Long time T1D here, I have had issues with severe site reactions over the years using both short and long acting insulins. I was put on the T-Slim to keep my reactions in check using Humalog. The thought by my endo was that it would only be 1 type of insulin in use, and delivered in small incremental doses, may desensitize my reactions over time. I’ve managed the ongoing reactions with Humalog using a T-Slim, but still get the occasional angry red lump at the site.
I’ve decided to take a pump break, and yesterday took my 1st dose of Tresiba, which so far I’ve not had any sign of a site reactions, I know its only my 1st dose, so fingers crossed… I am however having bigger reactions to the Humalog when taking bigger doses for boluses.
Do any T1D using fast acting insulin who also get site reactions notice a difference, lets say using Humalog vs Novolog, or any other fast acting insulins? I believe my sensitivity is to an insulin preservative issue (maybe metacresol?) which I believe is in all insulins, but maybe the various insulins have different amounts of preservative, causing more of a site reaction? Anyone who has these type of issues, and has any input on both which long and short acting insulin gave less site reaction would be appreciated.
TIA