Tandem Study: Control-IQ with Lower Target

Randomized, Crossover Trial of Control-IQ Technology with a Lower Treatment Range and a Modified Meal Bolus Module in Adults, Adolescents, Children, and Preschoolers with Varying Levels of Baseline Glycemic Control; Diabetes Technology & Therapeutics Vol. 27, No. 3 18 March 2025 https://doi.org/10.1089/dia.2024.0501

The study compares using a standard treatment range of 112.5–160 mg/dL to using lower treatment range of 90–130 mg/dL I like the inclusion of time in tight range stats. The study is small, n=72 for such a wide age range (3-52) and only ran for 2 weeks per target range so it doesn’t prove anything but it is a great start at investigating a lower range with current technology. Thanks @TJG for prompting me to google something that led to finding this study.

You’re welcome! What did I write?

6 of the authors are at Tandem. Maybe they’re considering lowering the target range for Control-IQ.

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Of course, otherwise they wouldn’t have published this.

72 participants aged 3–57 years completed the study

Wow. And none of the participants that completed the study died!

We can do better. We just need to agree to a protocol, a contract, to share our data in exchange for a portion, at least 90%, of the profits.

We have way more data than Tandem yet we are giving it away for free.

Our bodies in their detail are our possession. The cute world of Hollywood just woke up. Sorry, you haven’t been ripped off before! (Well, you have, but those who were never had the city block of lawyers in tow.)

Our data, our bodies, are the single thing we all have that can change the world but if we give our data away the world will not change. We need to protect our copyright then we need to change the world.

Tandem ran a self serving test of some hundred of participants and 72 eventually got their data ripped off. Every one of use who uses NightScout, or TidePool or has our own methods of recording off AAPS or, indeed, anything we use have more data that Tandem could ever profit from, though they would make a lot of money.

Collectively we know the answer and we have the answer. I’d like to see this happen but I do not know how to do it. Someone out there does; make us all profit for the benefit of everyone.

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Omnipod is doing a study doing that exact same thing. Lowering their lowest target from 110 to 100 or 90, they didn’t tell me which it was actually going to be, but they didn’t take me in the study because I was too well controlled. And they wanted people who could show a lot of improvement.
I was hitting 90-95% in range when they interviewed me, and they wanted people in the 70% range.
Good news it looks like they will be updating the ranges on all the pumps.

I’ve used both 100 and 90 with Omnipod and AndroidAPS (so not O5). At present I’m on 100.

What I seem to be finding is that when my insulin sensitivity goes up as a result of higher levels of exercise my control goes up massively too and 90 then works but with lower levels of exercise I’m much more sensitive to carb intake and I need 100.

Aaah, we should be doing this. It’s on a Discord somewhere I’m sure, but I’m way too old. We need young, motivated, T1ds not to help us (why should they) but to justify everything we’ve done.