I had a thought in the shower today (as one does). Two of the major obstacles to better glycemic control are the slow absorption of subcutaneously injected insulin and the delayed/less accurate blood glucose readings available subcutaneously. A healthy body can both infuse insulin directly into the circulatory system and detect blood glucose levels accurately. So why don't we inject insulin intravenously? And wouldn't a continuous glucose monitor with a probe in a vein instead of in subcutaneous tissue be significantly more accurate?
I suppose injecting insulin into veins might be too rapid, at least to allow single bolus injections, it might have to be trickled in, as the body does. But at least for a pump that would seem to be perfectly feasible. And while setting up an intravenous line is trickier than placing a subcutaneous infusion set, it's something with which plenty of folks with other conditions have to deal. I assume if a person with diabetes is checked into a hospital, insulin does get delivered intravenously (or maybe I'm wrong about that).
As for placing a CGM sensor in a vein, clearly there are various challenges and potential health risks associated with doing that, but I wonder whether it's something that's been explored much (and if not, why not).
Any doctors/RNs/others on here who might shed some light on this? For my part, I'm none of the above, the only formal medical training I have is as a former EMT, so these are just the musings of a diabetic who likes to better understand his condition and related issues.