Before and After Using Insulin in the 1920s

Wow. That child went from having a death sentence, to something more along the lines of a major nuisance.

Bravo, Mr. Banting & Mr. Best! :)

Oh my god. I'd heard the stories, and seen a segment on DLife, but that picture is almost unbearable!

Thanks Dr. Banting!! BTW he was Canadian!! :)

Here's an obituary for Dr Michael Somogyi, another important person that was instrumental in getting insulin to diabetics.

In 1922, while on the Faculty of Washington University
School of Medicine, in teamwork with Drs P. A. Shaffer and
E. A. Doisy, Dr Somogyi was instrumental in working out the
method for the preparation of insulin. This method is to this
day the one used all over the world for the commercial
production of insulin. The first child diabetic to be treated
with insulin in the USA was an 18-month-old baby boy in
the St Louis Children's Hospital in early October 1922, using
insulin prepared by this trio of researchers.

Thanks, I did not know about Somogyi's contribution.

What is even more interesting that the University of Toronto and or Banting did not patent insulin. I guess there was some morality in business then.

I had a great-uncle who was one of Banting's kids in the 1920s. He and his family lived in Saskatchewan and went to Toronto to see Banting because they'd been told that my uncle would live for about two years, at most, and slowly starve to death. Banting hoped to give him 5-6 years when he started him on insulin.

My great-uncle lived into his 70s. :-)

OMG.OMG. I thought it was bad in 1962. By the way, I looked as bad as pic 1 when diagnosed. It just gets me with little kids. I was 10, but......

Thanks for the start of the Discussion , Richard !!

A bit more info about Dr.Banting: Born on Nov. 14, 1891 in Alliston, Ontario
Married Marion Robertson in 1924
Died Feb. 21, 1941 in a plane crash at Gander, Newfoundland

1912 Entered Univ. of Toronto Medical School
1920 Established practice in London, Ontario
Lectured on endocrinology at the Univ. of Western Ontario and developed the link between diabetes and the pancreas
In 1921, went to Univ of Toronto and conducted reasearch with J. J. McLeod, C. H. Best and J. B. Collip
Jan 11, 1922 Banting first injected 14 year old Leonard Thompson with Insulin
Treated Elizabeth Hughes with remarkable results
Did not claim a patent for insulin - wanted to give it to the world
Banting and McLeod received the Nobel Prize for Medicine in 1923
Banting shared his prize with Best - McLeod split his with Collip
Knighted in 1934 - Sir Frederick Banting, KBE
Banting House Museum established in London, Ontario

Wellknown for his artistic capabilities as well .
Anthony posted a " LIKE " comment !!
I am aware of the " Somogyi effect" , however learned more , thanks to FHS about Dr.Somogyi and insulin being made available

Wow Ann what a great story, albeit one we don't really want to hear!

I think, when I'm having a bad blood sugar day (like I am today), I should look at this picture.

Even my worst blood sugar days are nothing compared to before insulin. Without insulin my blood sugar would be 1000 and I would be dead.

Can you patent a hormone produced by every healthy pancreas in the world?

Michael Bliss's books 'Discovery of Insulin' and 'Banting: A Biography' do a great job of explaining how insulin was discovered. The CBC ran a video several years ago called 'Glory Enough for All' that is just great.

Dr. Banting and Prof. McCleod received the Nobel Prize for the discovery. Dr. Banting shared his part with Charles Best and McLeod shared his with the chemist who really refined the insulin, James Collip.

It is an absolutely fascinating story. Check out the books and the video.

Yeah, we all learn about DP and the Somogyi Effect, but he did a ton of research back in those days.

Michael Bliss was a Speaker at last October's Canadian Diabetes Association AGM in Toronto, ON and I was priveleged to hear him speak about Frederick Banting

That's neat, Nell! I wish I could have been there with you.

Thanks for the references, I hope I can find the video.

Of course, one can nearly 'patent, trademark, register', anything it seems, of course insulin. OUR HEROES!

Children dying from diabetic ketoacidosis were kept in large wards, often with 50 or more patients in a ward, mostly comatose. Grieving family members were often in attendance, awaiting the (until then, inevitable) death.

In one of medicine's more dramatic moments, Banting, Best, and Collip went from bed to bed, injecting an entire ward with the new purified extract. Before they had reached the last dying child, the first few were awakening from their coma, to the joyous exclamations of their families.

The Nobel Prize committee in 1923 credited the practical extraction of insulin to a team at the University of Toronto and awarded the Nobel Prize to two men: Frederick Banting and J.J.R. Macleod.[51] They were awarded the Nobel Prize in Physiology or Medicine in 1923 for the discovery of insulin. Banting, insulted that Best was not mentioned, shared his prize with him, and Macleod immediately shared his with James Collip. The patent for insulin was sold to the University of Toronto for one half-dollar.

we all would be! makes me feel so's an eye opener for sure. also think about those who suffer with other horrible chronic diseases, MS, ALS, Parkinsons..ya know, that's NO walk in the park either. Diabetes sucks for sure..but, look what we have, albeit a beast to manage, at least we're alive and puttin' along, trying and trying and we keep trying.

Thank God for these men! NOW, let's find a cure, pretty please?!>???