How sad that nothing has changed on this living thread.
no Peetie, your wrong. We have now gotten on to 200 % and 300% gain in number of t2 and spread problem around the world.
Surprising no ones worried. This will really crater health plans, medicare, medicaid and care budgets in particular.
I wouldnât say nothing has changed.
I think you may have a communication disconnect Jims.
Peetie was referring to this thread, which was first posted by Craig on July 23, 2008 at 4:42pm. I very much doubt that âWe have now gotten on to 200 % and 300% gain in number of t2 and spread problem around the worldâ since that date.
Nor do I subscribe to the âepidemicâ alarmist media beat-up. Yes, there is a higher diabetes rate, and yes we should be concerned about the effects of the crap dietary advice peddled to the world by the USDA, but people rarely note that the diagnostic criteria for type 2 have been very significantly changed over the past three decades.
Even if nothing else had changed, the simple diagnostic criteria change from FBG of 8mmol/L(144 mg/dL) to 7 mmol/L (126) around the turn of the millennium has led to a substantial instant increase; I never hear of that in the press. Add the better access to medical care in many parts of the third world and you add another percentage.
Lets keep things in perspective please.
Cheers, Alan, T2, Australia
Everything in Moderation - Except laughter
fair dinkum mate. good response.
have a drink on me.
cheers.
I do think guinness is no doubt popular in Australia, but it is Irish. I actually like Sheaf stout, it has two key things going for it, it is a tasty stout and it comes in a decent size bottle (27 oz).
ps. Has anyone figured out the carb count for Guiness or a good stout? All I see are widely different numbers, but I count a pint as 15 g and seem to do fine even tho that is a pretty small figure.
LOL, I know, it was the tastiest beer on my hard drive! Iâm a huge Guinness fan since I noticed the Draft can boxes have the # of carbs on the side of the box!! Iâll have to see if I can track some Sheaf down.
Right on, Alan! Obesity may be increasing, leading to more unmasking of the Type 2 genes in people who wouldnât have shown it when they were living on the edge of starvation, but blaming diabetes on obesity is so misguided, because otherwise why are there so many VERY fat people who DONâT have Type 2? I am also very suspicious of graphs that extrapolate trends without looking at limiting factors. The incidence of Type 2 is much more likely to level out (or even decrease when dietitians get the message, and the unlikely event that the world population declines!) than to continue to grow in a straight line forever. Thatâs common sense.
I donât like the term âdiabesityâ â letâs throw that one out. How about âdiahysteriaâ as a replacement? 
There is a bit of variation on the various sites about the carb content; it's possible it is different in different countries. I work on 10gm a half-pint and 20gm a pint. For that reason I am a bit careful about drinking too much of it.
It is also my favourite, but only in draught. When I can't get it I order Tooheys Old, which is a local dark beer, not a stout. I have an occasional half with lunch or as a mid-afternoon tipple in lieu of a snack.
Cheers, Alan, T2, Australia
Everything in Moderation - Except laughter
I don't like the term "diabesity" -- let's throw that one out. How about "diahysteria" as a replacement? :-)
This blog on the subject is well worth a read: Diabetes reporting in newspapers
Cheers, Alan, T2, Australia
Everything in Moderation - Except laughter
I disagree.
The hunter gaterer gene /digestion track is very efficient and designed to bang along the bottom of energy/food supply and by that means self limit thru food supply quality limit and hard exercise getting that meal.
Todays endless supply of super efficient grain/rice/corn productrion by mega farms and modern techniques and genertically engineered better grains, rice, corn now provides a 24/7 supply of super energy foods.
Either one exercise burns it off or limits input but today a hunter gathere human is faced doing energy control management input on thie mega supply of high energy food or face type 2 diabetes due to rot out of body due to glucose backed up in body and extra higher levels.
So far the best sucess in fighting this mess is âsuper low dietsâ, bariatric surgery, lap band and intestine liner that really is hobbling the gut efficiency. All else has been crap shootâŚ
adding more insulin and or avandia actos without answering what is causing insulin resistance will gaurantee body rot out.
27 years on extra insulin techniques - starlix, actos et all have done nothing but make a mess.
present solutions are a flat earth dogged belief in do not confuse me with the facts - my mind is made up. It is time to shed all the shiboliths and get out and solve the problem.
Here is another research article why its not your fault. Till a better fix, check out metformin to help stop excessive glucose release.
Pitt team identifies key protein causing excess liver production of glucose in diabetes
PITTSBURGH, Sept. 28 â Researchers at the John G. Rangos Sr. Research Center at Childrenâs Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine have identified a powerful molecular pathway that regulates the liverâs management of insulin and new glucose production, which could lead to new therapies for diabetes. The findings were published online this week in Diabetes, a journal of the American Diabetes Association.
Usually, the liver stores excess blood sugar as glycogen, which it doles out overnight during sleep and other periods of fasting to keep glucose levels within a normal physiological range, explained H. Henry Dong, Ph.D., associate professor of pediatrics, Pitt School of Medicine. But in diabetes, the liver continues to pump out glucose even when insulin is provided as a treatment.
âScientists have been trying to find the factors that contribute to this liver overproduction of glucose for decades,â Dr. Dong said. âIf we can control that pathway, we should be able to help reduce the abnormally high blood sugar levels seen in patients with diabetes.â
He and his team have been studying a family of proteins called Forkhead box or FOX, and for the current project focused on one called FOX06. They found that mice engineered to make too much FOX06 developed signs of metabolic syndrome, the precursor to diabetes, including high blood sugar and high insulin levels during fasting as well as impaired glucose tolerance, while mice that made too little FOX06 had abnormally low blood sugars during fasting.
âIn a normal animal, a glucose injection causes blood sugar level to rise initially and then it goes back to normal range within two hours,â Dr. Dong said. âIn animals that made too much FOX06, blood sugar after a glucose injection doesnât normalize within two hours. They have lost the ability to regulate the level while the liver keeps making unneeded glucose.â
Other experiments showed that diabetic mice have abnormally high levels of FOX06 in the liver, he added. Blocking the protein markedly reduced liver production of glucose, although blood sugar did not completely normalize. Within two weeks of treatment, there was significant improvement in blood sugar and glucose metabolism in diabetic mice.
Tests with human liver cells echoed the importance of FOX06âs role in glucose production.
âThese findings strongly suggest that FOX06 has potential to be developed as a therapeutic target,â Dr. Dong said. âIf we can inhibit its activity, we can possibly slow the liverâs production of glucose in patients with diabetes and better control blood sugar levels.â
Co-authors include lead author Dae Hyun Kim, Ph.D., and other researchers from the University of Pittsburghâs departments of Pediatrics and of Pathology. The study was funded by the National Institutes of Health.
About the University of Pittsburgh School of Medicine
As one of the nationâs leading academic centers for biomedical research, the University of Pittsburgh School of Medicine integrates advanced technology with basic science across a broad range of disciplines in a continuous quest to harness the power of new knowledge and improve the human condition. Driven mainly by the School of Medicine and its affiliates, Pitt has ranked among the top 10 recipients of funding from the National Institutes of Health since 1997.
Likewise, the School of Medicine is equally committed to advancing the quality and strength of its medical and graduate education programs, for which it is recognized as an innovative leader, and to training highly skilled, compassionate clinicians and creative scientists well-equipped to engage in world-class research. The School of Medicine is the academic partner of UPMC, which has collaborated with the University to raise the standard of medical excellence in Pittsburgh and to position health care as a driving force behind the regionâs economy. For more information about the School of Medicine, see www.medschool.pitt.edu.
About Childrenâs Hospital of Pittsburgh of UPMC
Renowned for its outstanding clinical services, research programs and medical education, Childrenâs Hospital of Pittsburgh of UPMC has helped establish the standards of excellence in pediatric care. From Ambulatory Care to Transplantation and Cardiac Care, talented and committed pediatric experts care for infants, children and adolescents who make more than 1,000,000 visits to Childrenâs, its many neighborhood locations, and Childrenâs Community Pediatrics practices each year.
Childrenâs also consistently has been named to several elite lists of pediatric health care facilities, including U.S. News & World Reportâs Honor Roll of Americaâs âBest Childrenâs Hsopitalsâ and the Leapfrog Group. Also, Pediatric research programs at Childrenâs Hospital and the University of Pittsburgh School of Medicine ranked eighth in number of grants from the NIH for fiscal year 2010.
Mr. Peachy,
I can see your point. At some point we should take responsibility for our decisions. Whether we will drink soda or tea, eat another greasy cheese burger or a salad.....these are decisions we make for ourselves daily.
However, I realize too that our food choices are not what they use to be. Many times the crops are genetically altered and put into our foods without our knowledge. The long term effects of this is still being determined and argued. I found some interesting information about GMO here.
I totatlly agree that everyone should exercise on a daily basis......but most of us work and it can be a challenge to find the time. I love walking but admit I should do more of it.
I can understand a little better why diseases like diabetes, cancer and heart disease are on the rise when I educate myself.
So yes, we are responsible for our actions, but there are many factors at work here that are out of our control.
Right you are! The other thing you didn't mention is that there is SO much going on metabolically and different people are born with genetically different metabolic capacities, so some people CAN eat the greasy cheeseburgers, and sit on the couch without getting fat. Others can eat minimally and exercise and still get fat. Both of those extremes are really beyond our control, so we can work with what we inherited, but reality is reality.
The other thing that I think is REALLY important is to disassociate Type 2 with obesity, because they are NOT the same thing. Most (but not all) Type 2s are obese, but most obese people do NOT have Type 2. New research is needed to distinguish between 2 DIFFERENT diseases that have a symptom in common. I haven't heard much of anybody acknowledge that.
The real tragedy is that human body was optimized to protect against starvation and in fact there never was any optimization built in to protect against over supply of calories/glucose since in past scarce and low energy foods coupled with hard work - expended energy tended to limit the amount of daily available carbs externally to human body. Today, yes, human needs to directly manage energy input so as not to saturate body local glucose storage of the fat and skeletal muscle cells.. This has noting to do with obesity/body size or fat supplies but saturation of the local glucose stores of fat and skeletal muscle cells. The saturation is what causes the system to go out of regulation.
This saturation is further complicated by liver leakage from aging - and pancreas aging droping its basil pulses and offsetting the body setpoint creating extra glucose over and above diet considerations. and extent of physical exercise burning that glucose off.
Since genetic variations generally do not happen in one life time but over many cycles of that, the excess 24/7 quailty food availability has only been available since 1970's and on, we are reaping the reward.
Should the gloom and doomers be right and we have a full scale world economic crash, we may have opportunity to see this disease epidemic get starved out of the human system as food sources dry up.
As for blame, ridiculous. None of us growing up had any traininjg or thought about energy management and nor any real good reasons to do so prior to the 1970's.
I concur that the current fad to link body fat and obesity to be causitive agents of diabetes to be off track standing in dead end tunnel with lights turned off. I honestly believe that there is no difference in this case narrowly speaking between the type 2 obese diabetic and type 2 scrawny lean diabetic as both types have probably saturated their body's local glucose stores of the skeletal muscle/fat cells and energy equation out of balance. The obese person is just better able to convert more glucose to fat better than the scrawny person.
And it may still turn out that genetic damage - immune diseases may be a factor causing the set point servo system of the liver, pancreas, skeletal muscle/fat cells to get damaged and go out of whack and wander up causing cell glucose saturation faster and sooner as system ages over time. Presently the only real tool fighting excess liver glucose release is metformin coupled with carbs control and sufficient hearty exercise.
Actually the abundant supply of food was available in first world nations long before the 1970's, only interrupted by war-induced famines. Somewhere, I saw menus from opulent feasts put on by rich people in the 1700s and 1800s -- MUCH meat, and many courses -- I almost puked reading them! So why is this obesity epidemic only happening since the 70's?
Oh boy, here we go again.
I did not include that small part of the historical population in my discussion for a reason. The only folks who got a super loaded diet of unending orges were in fact the super rich - a small part of the population. That does not extend to the starving masses.
Same goes for the pharohs of Egypt. Those who supervised the building of the pyramids showed all the rot and body destruction found in the ancient mummies.
As those who did the actual building of the momuments 2 ton stone blocks at a time could not afford and generally not mumified but my best guess is they did not suffer from diabetes type 2.
Given the small set that could afford/get too much food, the actual impact of type 2 diabetes was probably limited to a small set back then.
I will repeat the argument I made that it has only been in these modern times of advanced science and production that has been able to make excellent rich food available to everyone is where we are seeing the numbers on type 2 diabetes explode .
Nobody said it was zero and Type 2 is a totally modern disease. Now what: history lessons? May I inquire just what point are you trying to make?
My point? Being my usual OCD, nitpicky self, LOL!! I tend to be a miniaturist, and focused on details. Sometimes I discover things that weren't obvious, but if I were 100%, I'd be God, not human! At least you get the real me! :-)
Here again only the super rich had the money and access to document their escapades while the other large portion of peoples who starved and made a lean living never got to document.
But who cares. Provide a solution to drop the serious expanding numbers of type 2 diabetics and stop arguing and putting me down.
I do not hear any reasoned science or thoughts suggested other than pick holes in my comments.
Wrong possibly, but I am clear what got my mess back on track and it was not the orthodoxy or cures of the last 26 years.
I was like you for 12 years. Then I had a hernia; my diabetes changed overnight. I didn't catch it soon enough. So get some insurance, even if you have to move to Canada to get it. And check your a1c regularly. Diabetes changes on you, but congrats on controlling it with diet and exercise. You'll feel better any way.