i mean if you dont’'t care about getting cancer keep using tresiba, just
don’t cry to me when it happens. the people who make it, sanofi aventis,
care nothing about keeping people alive. Did you know they make abortion
pills/??? and you TRUST them with your life? keep looking in the
internet it’s like hidden way in back on like the millionth page. I need
insulin to live, i’ll be damned if i use something made from a company whos
bottom line is abortion pills. Pro choice or pro life, you cannot deny
this. Of course if you want to trust them be my guest. I’d go back to NPH
if there was no levemir
levemir has NO peak, unlike lantus, where there is a 5-8 hour peak, and
levemir lasts longer, you don’t even feel it or the needle going in.
Lantus is very similar to NPH and you’re gonna get drug companies here
putting me down for telling the truth. I wish that Lente was still made,I
might use humalog, but i use regular for high fat meals you should always
have both. same with NPH I have dawn phenomonon, so besides my 80 levemir I
give 20 more nph in another spot. if my doctor knew this she’d kill me,
thank god you can buy regular and nph at wal mart over the counter cheap,
Had an a1c friday was 6.3
Umm, why would them making abortion pills make me distrust their insulin? One thing has nothing to do with the other… If anything it means I trust them to make medications for people’s for healthcare needs regardless of the politics of it, which IMO is a good thing from a medical care company.
Also, as someone who used NPH and then Lantus for many years each, they are not similar at all for me in how they act. Lantus was infinitely better and flatter than NPH. It’s great that you get good results with NPH, but for many of us, NPH was terrible and changing to Lantus was a life-changing and very freeing development. Personally, I can’t take Levemir because it gives me allergic reactions at injection sites (similar to what I also used to get with Lente insulin). I’m an example of why it’s always good to have multiple options/formulations to choose from, since inevitably some people will be intolerant of one or have better/different responses. I’m now using Tresiba, which I think is the best yet, but the difference is much smaller than the improvement I had in switching to Lantus from NPH.
[[quote=“cardamom, post:23, topic:57702”]
Umm, why would them making abortion pills make me distrust their insulin? One thing has nothing to do with the other… If anything it means I trust them to make medications for people’s for healthcare needs regardless of the politics of it, which IMO is a good thing from a medical care company.
[/quote]
Absolutely → to the above!]
I don’t generally reply multiple times to the same thread (unless I have learned some new info on the same topic in the meantime), but some recent posts on this one are just full of inaccuracies or speculations stated with such (unjustified) confidence, that I felt compelled to chime in.
On two specific items:
-
Levemir DOES peak, even if it’s a much less pronounced peak than that of rapid-acting insulins. From its own manufacturer: Levemir® (insulin detemir) injection 100 U/mL | novoMEDLINK™; from a neutral source: http://www.diabetesnet.com/about-diabetes/insulin/insulin-action-time. Bottom line, the slight peak happens around 8-9 hours after injection.
-
On the correlations between a given kind of insulin and various kinds of cancer: it’s complicated. Here are some useful articles (by no means an exhaustive list), but the bottom line is that scientists simply do not have enough evidence for either conclusion. Until we have more conclusive trials, how alarmed any one of us decides to be about their own prefered insulin depends on whether a tin foil hat is part of your wardrobe generally.
http://www.ingentaconnect.com/content/ben/cds/2013/00000008/00000005/art00002 (large metareview)
http://onlinelibrary.wiley.com/doi/10.1111/j.1742-1241.2009.02275.x/full (small metareview)
http://www.tandfonline.com/doi/abs/10.1080/13813450903008628 (in mice)
http://www.tandfonline.com/doi/abs/10.3109/13813451003631439 (in T1 patients, but a crossover study - ugh)
As a sidenote, there are also a number of recent observational studies (mostly by teams led by Zachary A. P. Wintrob) on patients with T2, but my reading of those is that they suggest that the same (as yet unidentified) mechanisms might drive both insulin resistance (=need for exogenous insulin use in T2) and some aspects of breast and ovarian cancer progression. To me this is a sufficiently different argument from the one made above, so I am not including any of those references, but if anyone is curious, you can look them up by the first author.
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Extreme care is required in interpreting fragmentary data, which at the present state of knowledge is all these studies represent. Correlation is not causation (repeat as necessary). A similar sort of hasty conclusion was reached concerning obesity and diabetes, and believed as gospel for many years. Now it’s looking more and more as though the two are both results of a common cause.
On the cancer question, it’s just too soon to form conclusions. Full stop.
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Tresiba is made by Novo Nordisk, not by Sanofi.
Actually I can - see above.
The way I see it, everyone should be allowed to be damned every damn way they want:-)
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I believe I responded to this allegation in a different topic*, but I’ll repeat it in summary here:
I looked up papers on the association of Lantus and pancreatic cancer, and found that the entire body of research since its release provides evidence that there is no positive association between use of insulin glargine and cancer. Type 2 diabetes, on the other hand, has a very high positive association with pancreatic (and some other) cancers, and this is likely why more patients in Lantus trials had pancreatic cancer than the general public.
This is one of the many reasons why people should try to understand the way science (and statistics) work, rather than take information out of context and draw wild conclusions and then repeat them online. The association of insulin glargine and pancreatic cancer has been very well studied, and there is no evidence that they are linked.
* edit: added the link to the other thread, because it has links to and quotes from peer-reviewed papers evaluating the claims of an association between insulin glargine and pancreatic cancer. This is the way I evaluate such claims: look up (several) papers on the topic; read the papers; and come to a conclusion based on the evidence.
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Seconding that. Switching to Lantus after NPH was like being let out of prison for me. YDMV is a good rule but saying there’s no difference between Lantus and that stuff is nonsense.
I ended up skipping the Lantus/Levemir revolution, as I made my switch from NPH+Reg injections, to using an insulin pump with Reg (before the days of humalog or novolog) !
I have Levemir in my fridge, as backup in case of pump failure, but hoping I don’t ever have to try it.
I have gone back and forth with humalog and novolog based on the insurance preferred status, and both have worked about the same, and both better than Reg via my pump !
That would be CaremarkCVS and yes, you are not far off the mark. My wife worked for them, and when they forced the change on me, I went into the hospital, near death twice. I traveled around the world non-stop for many years, never came close to passing out and as soon as I was forced to switch, it nearly killed me.
I backed WAY off my dosage and let my sugars average 200, then over several months dialed it back. Since my wife was caught in the massive CVS layoffs, we now have a different PBM and I am back on Humalog thank goodness. It makes a massive difference for me. And I do understand that this is a very personal reaction for each person.
1 Like