Wow - 300's. Man you must have big storage of glucose in your liver.
I was reliably at 238 to 240 in am wakeup. At midnight 100 to 120.
Classic Dawn Phe pain in buttsky.
Yes, and until I had my liver arrested on metformin ( a different approach not discussed much - but researched); I got the insulin resistance down.
I believe the issue is the liver constantly punching out way too much glucose regulary and especially at night which saturates the glucose temporary storage of the skeletal muscles while you sleep and insulin in body gets nailed either by hormones or excess glucose. Once muscles loaded ( one cannot yet exercise while one sleeps) so any extra glucose added just fills up the muscles till muscles do not want any more and hence insulin resistance.
The other unshared story is that insulin - a storage hormone is only useful as long as skeletal muscles have room to store more glucose. If not, the body down grades the insulin receptor sites to reduce glucose transfer till more room.
In fact the insulin will circulate like water thru your veins doing nothing or almost nothing until insulin resistance drops back down.
The human body is not an infinite glucose dumping/burning machine and simply adding insulin/actos does not guarantee getting rid of excess glucose in the blood system when glucose skeletal muscle temporary storage sites are filled to brimming full.
I realy do not accept the idea that things happen without reason.
The human body is a complex multi-oran multi hormone chmeical plant that does a bunch of complex manuevers and when one has diabetes, this mess gets worse.
Medical science ( with my thanks for all the great works that occur ) really needs to get out of the dark ages and better understand the processes and action that go on and how to cope better with them.
At the present stage, much of what happens does in fact appear illogical and for without reason with the human struggling terribly to keep riot contained after the fun activities.
Best wishes and thank you for sharing.