Eli Lilly touts data for concentrated insulin delivered via Insulet’s Omnipod tech

Eli Lilly (NYSE:LLY) touted data this week from a Phase III study evaluating its Humulin R U-500 concentrated insulin delivered via Insulet‘s (NSDQ:PODD) investigational Omnipod U-500 device.

The company reported that people with Type II diabetes taking Humulin R U-500 using the Omnipod device experienced greater A1c reductions and needed less daily insulin compared to adults using multiple daily injections to deliver high doses of insulin.

https://www.drugdeliverybusiness.com/eli-lilly-touts-data-for-concentrated-insulin-delivered-via-insulets-omnipod-tech/

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Would have liked to have seen real data in the link. The results from that study were predicted to be out in spring 2017. From my own experience, I agree with their press release. I was having significant DP and an A1C no better than 8% on MDI. After using an Omnipod for 3 months, my A1C dropped into the 6% range and the amount of daily U500 insulin dropped over 50%. My A1C is now in the 5% range with no increase in lows compared to MDI. Getting a steady basal dose made all the difference for me.
On an unhappy note, I hate to be cynical but U500 is very expensive so no wonder Lilly is touting success. It is still packaged in 20ml vials. I use mine way past the 40 day “expiration” date due to cost. Am blessed with great insurance but I hate the waste.

I am surprised because they haven’t even been approved for U-200 yet.

Seems like the U-200 would happen before U-500!

I know they’ve been talking about U-200 for a while also.

U500 has been around at least 40 years…

What surprises me is that they have not gotten U-200 approval yet, but are already working on Phase III with U-500.

The jump from U-100 to U-200 is smaller than U-100 to U-500.

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Could they be targeting T2s with insulin resistance?

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I have been hearing about the U-200 omnipod plans for quite some time (a few years ago, I think).

I think the U-200 and U-500 would both be the same idea - more insulin available in the pod - just of varying degrees.

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