Fiasp, a Faster Acting Insulin


#1

Fiasp is a faster actin insulin from NovoNordisk. Have any of you tried it? If so, what are your experiences with it?

"Adults with type 1 and type 2 can now choose Fiasp, which can be taken up to 20 minutes after starting a meal and still be effective. Fiasp (“fast-acting inisulin now available in US pharmacies. A quicker version of the mealtime insulin NovoLog, Fiasp was approved by the FDA for adults with type 1 and type 2 diabetes last fall.
Notably, Fiasp is the first mealtime insulin without a pre-meal dosing recommendation – Fiasp can be taken as much as 20 minutes after starting a meal, while other injected mealtime insulins are best taken 20 minutes before eating. This flexibility is due to the faster onset and offset of this insulin. (It is still strongly recommended that users take Fiasp before the start of the meal when possible, but the option to take it up to 20 minutes later does add extra flexibility when necessary.) Depending on the amount taken, Fiasp begins lowering glucose in 15-20 minutes


#2

I have not. But my bet is that my insurance won’t cover it even if I tried to get switched. I’ve changed jobs – and therefore insurance providers – three times in the past six years. Each time, I’ve been forced to change insulin because the new insurance had a preference for one over the other. (and therefore wouldn’t pay anything towards the other.)


#3

It’s made by the same company that makes Novolog. If your insurance plan has Novolog on the formulary, then it’s more likely they’ll cover Fiasp. If your insurance plan has only had Humalog on the formulary, then it’s highly unlikely they’ll cover Fiasp.


#4

I tried it and didn’t notice any faster action than with Humalog, and in addition to that, I had to increase the dose greatly over what had been adequate on Humalog. For that reason I gave up on it. For me it was less Fiasp than fiasco.


#5

I switched to Fiasp 2 months ago. I like it. I’ve had Type 1 for 20 years. As long as I use a good injection site it works very well in 1 hour. I like that it’s peak is over in 3 hours. Then I drop about 10-15 points an hour for 2 hours. With Novalog I was getting a sudden drop of 50 or more points in hour 5 after injection which was causing issues since my meal dose is around 6pm and I’m in bed at 9pm. Alot of lows around 11pm. Now it’s not a problem. My insurance (BCBS) covers some of it. There are no discount cards so I am paying $100 for a 90 day supply.


#6

My son (almost an adult) has just started using Fiasp in his pump (off label - so huge thank you to his endo for getting this approved). As a teenage boy who is very busy, always eating, up late at night, and always trying to be more independent, his blood sugars have been way too high over the last year (A1c of 9.5) so when his endo suggested a Fiasp trial, I was all for it. This is what has happened over the last 10 days: he is now 75% in range during the day (a big improvement), he doesn’t yo-yo up and down all day, his highs are not so high, and most importantly, when he is high, his blood sugars are coming down MUCH more quickly than with Novolog or Humalog. I know it’s only been 10 days but this is HUGE for my son. I will update after a couple of months of using it in the hopes that he has not had any of the other issues people reference.


#7

@dalajosa, Fiasp sounds like an excellent choice for your son. I hope it continues to work that well.


#8

I’ve used Humalog since 96, and only bought my first vial of FiASP a month ago.

Overall I far prefer the FiASP, for all the reasons you mentioned.

The big difference between FiASP and Humalog is much shorter peak time (actually stops upward sloping BG’s in 15 minutes) and shorter duration (effectively done in 3 hrs vs 4 for Humalog).

I also require 30-40% more FiASP per day than Humalog.


#9

Wow. That is totally unexpected. We definitely use less Fiasp than we previously used of Humalog or Novolog.

Which I assume (at least for us) is due to significantly fewer high BG episodes so we need less insulin.


#10

I have been using Fiasp for 6 months in my Pump. (I actually had to convince my Endo that Fiasp was available in vials). I also noticed that my total daily usage of insulin increased from 65 units to 74 units. However, my A1c was reduced from 7.8 to 7.2.


#11

I’ve been using Fiasp for about two years (Canada). I love it. It works much faster than other insulins for me most of the time. I haven’t noticed any significant dose change.


#12

I’ve been using FIASP in a pump for about 9 months. In addition to the reasons above, FIASP is a reasonable match to linear active insulin calculation my Medtronics pump uses.