So many choices today!

Did you know “there are 10 categories of sugar-lowering drugs. They all work differently, so doctors could prescribe several of them, and many do. That’s just for starters. People with diabetes often have other problems such as high blood pressure, high cholesterol, chronic pain, and depression. Those get treated with medications, too. And did you know that taking more than four prescription or over-the-counter (OTC) drugs regularly is called “polypharmacy.” Multiple medications can bring risks of negative interactions and side effects, inconvenience, and high costs.” - David Spero - diabetesselfmanagement.

There are a boat load of new options out there available to manage our diabetes just recently in fact. I am always curious at what is happening in the diabetes drug and product market. I am fascinated and also suspicious of the ever growing market and the speed of approval. I might just be old school and as I’ve said more than once probably just real lucky in that my products and meds have worked forever and continue to work. So I am not in the market for new stuff.

My main health care crew seems to be an oddity because they don’t push / promote / provide new products when I go for doctoring. I asked my long time doc once about a new product (suggested by a specialist) for something other than diabetes. She told me that the new drug is not one she would prescribe because the one I use is has been available since before either of us were ever born, and she would never prescribe a new product. She also thanked me for telling her about this suggestion. That drug was not approved for my trouble at all! Guess who crossed that specialist off their lists.

Anyway - I was enjoying some banter about my cynical ideas with docs handing out new products to folks. And I went looking around at what is available for us diabetics 2014 - 2015. Here is what I found (and these are just the treatments) -

Jardiance (SGLT2) inhibitor from Eli Lilly Aug 2014 is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes It works by blocking the reabsorption of glucose (blood sugar) by the kidney, increasing glucose excretion, is the only diabetes medication to show a significant reduction in both cardiovascular risk and cardiovascular death in a dedicated outcome trial

Toujeo (insulin glargine U300) from Sanofi Spring 2015 is a long-acting insulin used to control blood sugar in adults with diabetes mellitus, contains 3 times as much insulin in 1 mL as standard insulin (100 Units/mL)

Tresiba (insulin degludec injection) from Novo Nordisk Sept 2015
a once-daily new-generation basal insulin analogue with an ultra-long duration of action, discovered and developed by Novo Nordisk. Tresiba® has a distinct, slow absorption which provides a flat and stable action profile.

Ryozodeg (insulin degludec/insulin aspart) from Novo Nordisk Sept 2015
contains Tresiba®, a once-daily new-generation basal insulin analogue in a formulation with a bolus boost of NovoRapid®. Ryzodeg® is the first and only soluble insulin combination of Tresiba® and the most prescribed rapid-acting insulin.

Afrezza (a rapid acting inhaled insulin) from Sanofi Summer 2015

YAY - we can now live forever!! LOL Please do remember that new drugs do sometimes end up on the list of drugs removed from the market because it was found to be potentially harmful and Oops some folks even died.

I hope that the hoopla remains hoopla, the success with these products continues, and that no harm comes to anyone. I would also like to thank anyone who takes a chance to try new stuff. Nothing wrong with that!

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I get the impression that doctors don’t monitor polypharmacy closely. In fact, it’s a topic I always bring up to the pharmacist when picking up a new prescription.

I mostly use rapid acting analog insulin and add Afrezza for the occasional correction and food party. I am irritated when pharmacy benefit manager tries to change my brand of insulin to suit their business model.

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