All I can say is I am here to relay the experiences of my TI G/F to spread the word and hopefully help people. This is the first major development in insulin therapy in decades and I’m excited about her results. Selfishly, if you will, we want this therapy and company to survive so she can continue to enjoy her improved results. I am happy to help anyone with questions about transitioning to Afrezza because it take effort knowledge and practice to do so. If you believe my time here is only for financial purposes you might check my Twitter account and realize my employment situation is counter to that opinion. I have a much greater financial interest in a competing company. Don’t hesitate to ask me for help. I’m happy to help.
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I use Afrezza and am a HUGE believer in it being a total T1D game changer. It works so much faster than anything else. I use it with Tresiba, which is a huge improvement over Lantus. I no longer need to take insulin when I wake up in the morning and go first to the gym–with Lanrus I would always spike. I use the Abbott Freetyle Libre which is a very slim and easy CGM. It doesn’t make me feel overly wired up. If you know anyone in Europe they can get it for you, otherwise it should be released in the US sometime in Q1 of 2017.
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It’s near unanimous… You’re either on the insulin regimen of the future (tresiba and afrezza) or you’re living in the Stone Age! Glad to hear from you!
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…or living in Canada where neither Tresiba or Afrezza are available. 
That is the first time I heard Canada called the Stone Age.
I have been searching the Health Canada (like the FDA) website for drug approvals once a week, every week but haven’t seen insulin there yet. Maybe I should get proactive and just email the manufacturers.
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Maybe some petitions to whoever the regulatory authorities are would be helpful.
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so I am now on toujeo 70 split into 12 hour incriments and on afrezza 4 units and some times I have the same situation. one day I will be in the mid 200 an the next day I will be in the mid 100 . so I am wondering is 4 units enough to cover my weird spikes and lows. have been on afrezza 4 units for 3 weeks now. I now that is not enough time to evaluate the effectiveness of afrezza. but I need to know as i will be seeing my endo who is also type 2 diabetic, refered me to afrezza tommorrow. so i need to know what adjustments to make if any. also on once a week trulicity as well as well as invokana 100 . So what to do is my question. need some suggestions and advice .
Well I can tell you that 4u are pretty ineffective for me unless they are used solely for a corrections n without food for me-- and I’m a type 1, not characterized by insulin resistance (whatever that means)
For even relatively moderate carb meals I need an 8 and I find that timing of the dose is paramount and also my activity level afterward makes a big difference (just as it does with injected insulin). Frequently even with a moderate carb meal I’ll end up taking an 8 and then following up with a 4 a couple hours later— and im a 175lb type 1
If you’re at 200, say about 2-3 hours after a meal what happens if u take a 4?
I agree Sam. If you are still high 1-2 hours after taking Afrezza simply take another four units. We test every hour or so after complex meals and take more Afrezza if BS is high.
Vibes… I don’t think it’s user input. I had type 1 diabetes for 27 years so far and my HbA1c hovers +/- from 8.0 but never under 7.5. When you have diabetes for so long… you have many stretches of user input where you’re motivated to try extremely hard for 6 months and still unable to make much difference in the HbA1c and then have stretches where you lose motivation. With Afrezza it would probably be the opposite of user input because its that much better that you could slack off more. I started Afrezza October 1st and its still tricky without a CGM because the basal of a once per day flatline basal like Tresiba doesn’t help when dozens of spontaneous factors can mess your basal blood sugars up. Many are using CGM + Afrezza as a basal correction plus bolus for meals. But keep in mind that even though Afrezza can bring blood sugars down fast, nerve damage is being done with highly volatile blood sugars, even if you bring it down fast, the fact it got so high contributes to nerve damage even if briefly up. So the goal has to be to keep it below a highest target level. CGM would help with that. I’m not on the CGM yet and my conclusion is that Afrezza is good but can be way better combined with CGM. Also… did you guys see the news today! The FDA just approved the Medtronic MiniMed 670G which is an artificial pancreas combined with CGM for the basal. The artificial intelligence algorithm and automation is only for the basal. But if you use that to perfect the bassl and Afrezza only for the meals… that would be the closest to a cure you can get! Other than a biological cure or smart insulin.
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I agree with you completely! We will get a CGM this week! I’m very excited to see what effect it will have. I feel confident that it combined with Afrezza will be great. I will update with results.