Just wondering if anyone has had gastric by-pass surgery and been able to reduce their meds/insulin before the weight loss kicks in? I have been following the Stampede study out of the Cleveland Clinic which shows that the surgery alone seems to assist Type II diabetics in managing their diabetes, in some cases as quickly as a day after the surgery. Just wondering if anyone has had personal success with this surgery?? Here is a link to the study:
https://weightloss.clevelandclinic.org/ClinicalTrials.aspx
You might try checking out this group Gastric Bypass the last resort. It is a group dedicated to Gastric Bypass.
It looks like the group has been idle for a while but there are past post where with good information. You might try posting there, who knows you might wake them up.
University of Newcastle upon tyne - MRI center and Dr Roy Taylor have been doing testing using mri spectography on extreme 600 calorie diet watching the pancreas and liver and their read was that these two organs come back to working correctly by getting the fat out of pancreas and liver. This occurs well before any major body fat loss. Their suspicion is that bypass surgery achieves the similar result.
1345-NewcastleMagneticResonanceCentre.doc (46.5 KB) 1346-Type2Diabetes_R_Taylor_u_of_newcastle.doc (463 KB)Hey thanks Gary...
thanks for the info Jim....sounds interesting
Hi Photomkr and Welcome!!
Our Tud Friend Grant took this path and he was doing Great the last we heard.
Big difference.
http://www.tudiabetes.org/profiles/blogs/3-yrs-from-roux-en-y-never-better?xg_source=activity
http://www.ontariobariatricnetwork.ca/Roux-en-Y-Gastric-Bypass-Surgery.aspx
Perhaps you can send him a pm and ask him to relate his experience to you also. There is always hope. Good luck in which ever you choose to do.
here is another study looking into type 2 islet and liver insulin resistance recovery by separate group in UK .
Title is :
Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol
Summary says:
However, type 2 diabetes is clearly reversible following bariatric surgery [7]. The normalisation of plasma glucose concentration follows within days of surgery, long before major weight loss has occurred, and it has become widely assumed that the protective effects of gastrointestinal surgery are mediated by altered secretion of incretin hormones [8, 9]. Improved control of blood glucose in type 2 diabetes by moderate energy restriction has been demonstrated by others [10]. We have hypothesised that the profound effect of a sudden negative energy balance on the metabolism could explain the post-bariatric surgery effect [11] and, specifically, that the decrease in the intracellular fatty acid concentrations in the liver would lead to a lower export of lipoprotein triacylglycerol to the pancreas, with the release of beta cells from the chronic inhibitory effects of excess fatty acid exposure.
and:
Discussion
This study demonstrates that the twin defects of beta cell failure and insulin resistance that underlie type 2 diabetes can be reversed by acute negative energy balance alone. A hierarchy of response was observed, with a very early change in hepatic insulin sensitivity and a slower change in beta cell function. In the first 7 days of the reduced energy intake, fasting blood glucose and hepatic insulin sensitivity fell to normal, and intrahepatic lipid decreased by 30%. Over the 8 weeks of dietary energy restriction, beta cell function increased towards normal and pancreatic fat decreased. Following the intervention, participants gained 3.1 ± 1.0 kg body weight over 12 weeks, but their HbA1c remained steady while the fat content of both pancreas and liver did not increase. The data are consistent with the hypothesis that the abnormalities of insulin secretion and insulin resistance that underlie type 2 diabetes have a single, common aetiology, i.e. excess lipid accumulation in the liver and pancreas [11]. This provides a unified hypothesis to explain a common disease that previously appeared to require separate disease processes affecting the pancreas and insulin-sensitive tissues.
Attachments:
Thanks Terrie, this gives me hope. I just wish it didn't take so long to get the surgery. My Dr. has gone through the referral process but I understand it can take upwards of 3 to 4 months before you even hear from the clinic that you have been assigned too and then another year before you get the surgery. I realize we are lucky to have the procedure paid for here in Canada and I certainly appreciate that but the wait for something that could save my life is just ridiculous.
Hi Jim, thanks very much for this info...exactly what I was looking for.
YW! Yes, it takes that long since the Dr./Patient ratio is so off balance here
like in most countries. We need more Drs! I was wondering what people were talking about when waiting to get to see a Specialist. WELL, I understand now.
In Feb. I was referred to a Specialist for a non-D related problem. I was scheduled in May to just talk to the assistant/answer questions and run some tests. I was given my appointment with the Specialist for next MARCH. I replyed in shock,"You've got to be kidding me"!! Fortunately, the assistant suggested that I get on the cancellation list since it was an important problem and some patients can't make their appointment for whatever reason. I was called and got an appointment in Sept. instead. Problem solved!
Do you thnk you could get on a cancellation list also? Some patients do decide not to have surgeries done on occasion. But make sure that they do not cancel your original scheduled appointment. Or perhaps you are already on this list.
I think that some patients are still being transferred to the U.S. for this surgery although they charge Canada, 3 times the price. You still wouldn't pay for it.
I hope that you get this figured out and an earlier appointment, so this will just be a major, successful event in your past. That certainly is an interesting article that Jims posted. Makes one rethink things.
I understand why some people get the surgery, but why go through all of that though?
I look at it as a tool to fight the complications of diabetes. I have a BMI of 44 and suffer from peripheral neuropathy, cardiovascular autonomic neuropathy and have suffered a minor stroke within the last year which make it difficult to get enough exercise to lose the massive amount of weight which I need to lose. Being only 46 years old and having a family I need to do whatever it takes to delay the inevitable and this surgery is one of my options. Add to that the various studies showing more and more that this surgery can reduce or eliminate the need for insulin and medications for Type II diabetics even before the weight loss kicks in. I don't think it's for everyone and if you are able to manage your diabetes with diet and exercise and have no major complications then it probably isn't the right choice but in my case desperate situations are cause for desperate measures.
Unfortunately Ontario changed the process to get Bariatric surgery back in 2009 and now your doctor has to refer you through a central referral portal which eliminates the possibility of getting on a cancellation list or jumping the line based on your medical situation, which is really too bad in my opinion. You have to be processed through a provincial "bariatric centre of excellence" of which there are only 4 of in all the province. I understand the need to have a formalized process but this one seems to be lacking the resources needed to be efficient which is an unfortunate but expected result within a public healthcare system. Don't get me wrong I'm not complaining as I certainly don't have the means to pay for it myself, I just wish I could get it sooner.
My Sister in-law had the standard Gastric bypass 8 years ago and was taken off insulin and pills that day. She was using over 600u a day when she went to the hospital. She now suffers from Hypoglycemia every day , osteoporoses, and other nutritional related disorders. She had no other choice, except death, she just could not stop gaining weight and was no longer ambulatory. The Gastric bypass was not a cure for her chronic illness...just a different treatment plan, she still has several forums of chronic illness.
thanks for sharing John. I agree totally that the surgery is not a cure but rather a tool to fight obesity.
Yes, I believe one can and its the 600 extreme calorie diet done by the University of Newcastle upon Tyne crew and their MRI spectography science work and they specifically believe that both approaches achieve the sudden removal of excess glucose generation that in my opinion helps de-saturate a type 2 body that has been running too long with excess glucose release and no where to go.
1342-Type2Diabetes_R_Taylor_u_of_newcastle.doc (463 KB) 1343-NewcastleMagneticResonanceCentre.doc (46.5 KB)