My Doctor wants me to take Glimepiride along with my Metformin. I'm scared to take it because of the side effects (no long exposure to the sun...my kids play a lot sports...I'm in the sun all the time; the neuropathy side effects...I'm afraid the tingling in my fingers will become permanent.) My fasting blood sugar, after a week of low carbs and 500 mg 2 times a day of Met, is still in the 230s. I'm also walking 20 to 30 minutes each day. I have not taken the Glimepiride at all yet, mostly because I'm afraid to.
I took Amaryl with Metformin with no ill effects, but we're all different. You can always stop it if you have problems.
Just a question: Have you been tested to make sure you are in fact, Type 2, not type 1? Some questions to consider would be: Are you overweight? Do you have another autoimmune disorder such as thyroid?
Well you have to do something about your blood sugars. I am surprised your Doc did not try the maximum dose of Metformin, which is 2000mg/day before moving on to other drugs. Metformin has been used a long time and is considered very safe, all the others have various problems associated with their use. If the drugs turn out to be totally ineffective I would suggest getting some antibody tests done to make sure you are not LADA