This is what my Endo told me regarding Levemir:
“It has not been approved for use during pregnancy yet.” They are doing studies for the past 5 years and haven’t found anything negative about using Levemir during pregnancy, but won’t release the green light for use during pregnancy until 2012. On the flip side, Lantus has been proven to interfere with the baby’s growth hormones during pregnancy, so many Endos will not approve usage of Lantus during pregnancy.
Personal Experience: I used NPH in place of my friend Levemir during the first trimester. Switched back to Levemir during second trimester and so far so good. Most of the baby’s vital organs are done being created after first trimester.
I am not aware of any studies regarding Novolog. Many Endos are not concerned with the effect of short acting insulins on the fetus because the insulins leave our bodies from 2-4 hours later. From what I know of concretely, Humilin R is the only approved for pregnancy.
Personal Experience: I’ve been using Apidra with no issues
Regarding Symlin- From what I understand, Symlin is similar to Metformin in that it helps to maintain weight control and to lower short acting insulin dosages while increasing insulin absorption. Symlin is an injection while Metformin is a pill.
From what I’ve read, Symlin is a newer drug while Metformin has been around and in use since 1920 (before most insulins).
Personal Experience: I’ve never used Symlin. I was on Metformin in 2010 to help with major insulin resistance. I used it for 3 months and then took myself off because my BG control improved greatly. I resumed using Metformin to help combat the insulin resistance during the second trimester of pregnancy. I’ve been using Metformin for one month and my BG control has been relatively fantastic. No issues so far. I have no experience with Symlin.
Breastfeeding: While breastfeeding, BG has to be in range (or at least under 200). If out of range, usually discard the milk pumped. I’ve read studies and have heard stories about Type 1 pregnant women (also pregnant Endos) using Metformin during and after their pregnancies, while breastfeeding. I don’t know any studies regarding Symlin.
I hope this helps. Didn’t mean to ignore you for past few days- just didnt see this post!
~ Type 1 for 13 years, 20+ shots per day, Metformin, no CGM, no pump, 7 months pregnant and counting