I would try this for sure. I imagine its absorption may be even faster than an injection, and it would be easy to use. It will be interesting to see which becomes more popular, this or the auto-injector.
I wonder if it will be useful for mini-dosing, or just as a full rescue dose.
I also wonder if having allergies or a cold (I have pretty much constant allergies) would interfere with its absorption.
I don’t understand the purpose. Is this for self-administration, or if someone is unconscious?
It’s all in here - who does what etc
I followed the link but I’m uncertain if the packaging contains many rescue doses or just one. It did not mention using the product as a series of mini-doses to help with blood glucose management.
With this Lilly product and the products from Xeris and Zealand, I feel like there’s healthy competition to get this product to market. The next test will be the pricing. I fear it will follow the path of greedy insulin makers.
I would hope it will be like the pens that are in trial and can be used for mini dosing. I think these mini dosing options are going to be great. Can’t tell you how many times, I need to eat more and just can’t or don’t want any more but blood sugar is calling for more carbs. This could help so many over shooting the mark. Again, as is everything in diabetes treatment options, will it be covered and how much will it cost. But this is making me very excited for dual hormone pumps coming in the future.
Unfortunately, this link Lilly submits NDA for nasal glucagon says that it is a single-use device.
That single use proclamation puts to rest a series of treatments. It will come. It’s a question of when and how much it will cost.
You bet, I am ready for some Glucagon (spray)
I would definitely want some for my son to have at school. Here in Washington state schools only allow a school nurse to give a shot of any medication, even glucagon. This means, in a life threatening emergency, no other school staff is permitted to administer glucagon, the school staff must just wait for the EMTs! Plus due to funding the nurse isn’t at the school full time. So even though my son carries a glucagon no one is
permitted to help. Having nasal glucagon would be a work around for this ridiculous rule.
I would suggest write to all of your state Senators and Congressmen. Ask them to revise the law. There are many other states which have updated laws on the books to cover this. There is no reason for a state like Washington to be so far behind. It does not make any sense.
In our state, the law allows trained school personnel to administer glucagon without requiring that person to be actual medical personnel. The school nurse is able to train other school employees and they are then covered under the law. To me, this seems so reasonable as to be surprised the state was able to pass something like this. This is relatively new to our state just a few years back. It has many other aspects in it like allowing the students to be protected by state law to do such things like: treat a low (duh), check their bg (duh), carry their supplies (duh) - things that you ask yourself - wow - we needed a law for that? And a provision that rather than set a fixed age (which would be stupid - anybody knows how different kids are in what they can or can not do and they are not all the same) it is doctor based and if the doc signs off that the child is able to do the various tasks then the child is covered under the law. Really awesome.
So point being. Washington does not even have to start from scratch. Simply take a look at the other states for laws already on the books and take the best parts or maybe one state has a complete law that would be a good match for Washington and use that?
But the lawmakers in Washington can fix this. One might even say that is their job.
The question is will this nasal spray work when administered to an unconscious diabetic? Perhaps yes because the glucagon spray in the nasal passages of an unconscious person will still be absorbed.
A clinical trial participant described in detail how to use this product.
Here in PA EMT’s could not administer life saving meds, but they could ask any joe blow walking by to do it without any liability on Joe Blow no matter the outcome - the rule has since been changed.
Unlikely I’d buy that. Also unlike that I COULD AFFORD IT! Look at how much current Glucagon kits cost even with insurance. The copay is super-high.
There has always been a strong tendency in medicine to punish diabetics, from the positively harmful exercise treatment used in France in the 1880s, when diabetics were pushed into acidosis by being forced to race up and down stairs while producing no insulin, to Allen’s starvation clinics in New York in the 1920s, which killed more patients from cachexia than they saved from acidosis. The same thing is true in modern treatments for hypoglycemia, from glycogen tubes providing the patient with hideously bad tasting sweets for low blood sugar to now forcing glucose up the nose, instead of using a simple and painless injection. Anything to make the patient more uncomfortable.
It’s NOT glucose up the nose, it"s dry glucagon powder up the nose, like affrezza I suppose. Read this article.
I read your posts and take interest in your different opinions. And sometimes your posts have useful thoughts and merit. But this post is silly.
The only think that would be forcing them to have stuff put up their nose is because people do not have the awareness and knowledge and calmness to inject.
This is not medicine punishing anyone. You will still be able to get injectable glucagon. If you don’t buy this, nobody will stick it up your nose.
But if a diabetic thinks his co-workers would become too panic-stricken to inject, he or she can give them the nasal option.
It is just a choice, a different option. It is not a requirement or a “punishment”.
Whether powder or fluid, it sounds equally unpleasant. I mean, how many people use snuff nowadays? I’ve also always wondered why glucose tubes were ever invented, since they don’t work any faster than eating a delicious piece of cake frosting and they taste absolutely awful? There is a suspicious instinct here on the part of the medical profession which I don’t like.