I used Levemir, but when comparing it against Lantus, I disliked the Levemir pen - the injection quality was less certain - and the action of Lantus was a bit gentler or prolonged, so less risk of overnight lows.
From what I remember, you have pretty tight control, e.g., < 6, so wondering if you use a pump. I’m thinking that your tight control makes Tresiba more tolerable. I might need a bit more flexibility to dose with 2 separate shots.
Yeah, I think Levemir has more of a peak than Lantus. I’ve never used it though.
Dose changes with Tresiba weren’t visible for a really long time for me - longer than other people have reported. It took about 36 hours for the new doses to really be noticeable. You may not have this problem. If your basal needs are pretty steady from one day to the next, then you’d probably really like Tresiba.
Or you can use Basaglar if you just want to stick with what you already know (Lantus).
Hopefully some other folks will report their experiences.
I tried Levimer after my insurance company stopped letting me get Lantus which I had taken for years. Levimer is one of the few insulins I have used that didn’t work well for me. I can’t remember why. After trying Levimer I tried Tresiba. My insurance company eventually said that they wouldn’t cover Tresiba anymore and that I needed to take Basaglar. My GP told my insurance company that Tresiba worked extremely well for me, so the insurance company said that I can use it.
I rarely change my dose of Tresiba, because I find no reason to. My carbs, exercise and weight rarely change. I do change my Novolog but not my basal insulin. It may sound funny, but only taking one shot of Tresiba instead of 2 of Lantus is a very big deal to me even though I don’t mind taking many Novolog shots a day.
My experience with Tresiba is now five years old. That’s when I switched to DIY Loop. I was so impressed with its performance that I tried to do an “untethered” protocol when starting Loop. That didn’t last but it was not Tresiba’s fault.
If I decided to go on MDI, I would choose Tresiba as my basal insulin. One of the things I really liked about it was that you could forget taking a dose and still take it 8 hours later with no apparent disruption in your glucose control.
I took my daily dose in the evening and when I forgot, I could just take it the next morning and resume my evening dose that same day. Of course, your situation can differ and experimentation is the best teacher.
Then one thing I had to learn is that due to Tresiba’s 42-hour nominal duration, you had to let 2 or 3 days elapse when you increased/decreased your dose for better performance. The day to day overlap eventually produces a “steady state” for your basal. Patience is not my strong suit so this required some effort on my part.
I gave injections for well over 50 yrs before switching to pens. I love pens and wouldn’t want to go back to using vials and syringes. Pens are just so very easy and quick. Yes, the needles do need to be changed, which I found out the hard way, but I still don’t change them after every injection.
I use a very tiny needle and rarely feel the injection.
The pen takes up very little room in my purse, so it is just grab and go. Also using a pen is less noticeable to others than using a syringe when I am in a restaurant. Someday I hope to go to restaurants again.
One benefit of pens over vials+syringes, would be if you are taking a low dose, such that you never finish a vial before it’s “use within 28 or 30 days of opening” recommendation common for analog insulins.
A lot of us regularly broke the 30 day recommendation. For example my basal is 20 units a day or lower, so I was using the same 1000ml vial for 50 days. If I had been following the letter of the 28 day rule I would’ve been throwing away almost half the 1000 units in each vial.
Pen: super convenient and unobtrusive. Can carry in your pocket ready to use. Insulin is already loaded, saving you that step. Back when I was injecting many times a day, I would reuse my needle, perhaps changing half way though the pen fill. I have one pen that allows half-unit increments.
One thing I never did was inject through clothing. I would be concerned about introducing foreign material. But I did not alcohol swab and all that: just inject (5 seconds) and carry on with my life.
I have been injecting through my clothing for over 40 yrs and I have never had any kind of skin infection. I am pretty sure that I heard Dr Bernstein say that he does this also. Of course when I was first dx in 1959, I followed all the steps including using alcohol.