Are there any T1D’s out there who could share experiences using Tirzepatide, Mounjaro, or Zepbound?
I’m particularly interested to know if you’ve noticed any increase in dawn phenomenon or highs after eating or intense exercise.
I ask b/c GIP-agonism by tirzepatide can stimulate glucagon production. That isn’t a major issue in T2D b/c it also stimulates insulin production which inhibits the effects on glucagon. I’m wondering what happens in someone who doesn’t make insulin.
Thanks for sharing!
I used Mounjaro for several months and lost 20 lbs. Of course, my blood sugar was lower, and my A1C went down .3 - .4 over a 3-month period. I also used less insulin, as you eat less. However, I would probably never use it again, as eating became unfun. I would go out to eat and be full after a few bites. Also, I had a lot of stomach aches the first few days after a shot. If you want to eat less but have stomach issues, try it.
Thanks so much for sharing - there’s surprisingly little info out there on this drug in people who don’t make their own insulin. It sounds like it really improved your blood sugar!
Do you think it made for fewer/lower BG spikes overall? I’m considering it for weight loss rather than BG control, but I don’t want to take something that might make BGs more difficult to control.
My Dr actually recommended Mounjaro/Tirzepatide over standard GLP1 drugs b/c it’s supposed to cause less stomach problems. I guess maybe there’s no winning there.
Your blood sugar will be much better controlled purely from eating less food. Your insulin needs will also decrease due to a lack of food intake. If it did not make food so unappealing, I would still be on it. One of my joys in life is eating good food with family and friends. When talking this shot, food was not enjoyable.
Interesting - I think that enjoying food less to some degree might help me to lose weight. I can definitely see that going too far, though. Did you find this to be a problem even at lower doses?
Sorry just saw this, at all doses I got nauseated and did not feel well the first few days after taking the shot
Started Zepbound a few weeks ago. It’s been…an experience.
Thus far, I’ve lost about 10 pounds. I just found my scale, so I had to compare it to the weight they took the last time I was at my endo’s office. That’s when they prescribed it. I’d been on Invokana before, but they had to take me off of it due to a reaction to something. I’m pretty sure the reaction was to something else, but they took me off of Invokana to err on the side of safety.
Zepbound zapped my appetite immediately. It also destroyed my insulin resistance, which is a good thing. In fact, I had a bad ride with that last night as I took too much insulin, overcorrected with juice and went too high, and then had to correct that. It was a wild night.
I do have side effects of lingering nausea and headaches. I don’t have nausea and headache, so I know these are side effects of this drug. It’s not fun. I’m also in a period of high stress, so I think that has something to do with it too.
All in all, I’m glad I’m on it, but I’m definitely adjusting to it. I’ve gone from 2.5 mg up to 7.5 mg. I think I’m going to ask them not to increase me this time and let me go another month on 7.5 as the side effects have been more intense, so I want more time to adjust. Then once things level out, we can go up to 10 mg.
No dawn phenomenon increase, but I also cover that with my basal rate. I’ve adjusted all of my insulin rates down significantly since it’s just destroyed any insulin resistance I had.