Incredible over-night – almost too good to believe
Last night was my fifth daily dose of Tresiba. I started with 14 units and finally stepped up to 20 units last night. I used Dexcom Studio to display my BG line from my 9:00 p.m. dose last night until I woke up this morning. I ranged from 81 mg/dl (4.5 mmol/L) to 114 mg/dl (6.3 mmol/L) over an almost 10 hour period. That’s 100% time in range and no hypo time. The standard deviation was about 8 mg/dl (0.44 mmol/L). That means that two thirds of my BG data points were within 84 mg/dl (4.7 mmol/L) to 100 mg/dl (5.6 mmol/L). My average BG was around 92 mg/dl (5.1 mmol/L).
My target range is 65 mg/dl (3.6 mmol/L) to 140 mg/dl (7.8 mmol/L). When I think about that range I further subdivide it into three zones, C (good) – 120 mg/dl (6.7 mmol/L) to 140 mg/dl (7.8 mmol/L), B (better) – 100 mg/dl (5.6 mmol/L) to 119 mg/dl (6.6 mmol/L), and finally the A zone (best) – 65 mg/dl (3.6 mmol/L) to 99 mg/dl (5.5 mmol/L).
Last night I spent most of my time in the sweet spot, A zone, with the balance in the second most desirable area, the B zone. Incredible.
When I was on my pump, this kind of overnight graph occurred a few times each year. Since this was only my fifth dose of Tresiba, I’m thinking this kind of line is possible much more frequently. If this is true, then Tresiba is a game changer for me. For me, the overnight BGs almost always correspond tightly to my waking BGs. I’m hoping that I’m not getting ahead of myself and that this is not too good to be true!
Thanks, Mike. I find it interesting that Dr.Ponder has been on Tresiba for the last three months. I look forward to his comments at the Diabetes Unconference next month in Las Vegas.
Your experience confirms to me that last night was no fluke. I am psyched! This can take my control to another whole level of dominance. Diabetes in my life is shrinking.
Sweet! Terry - congrats. I just started my first injection and things are looking good. I’m doing 26 units in my thigh - left a small mosquito bump - then proceeding with my normal day - i did leave my pump on at 50% basal reduction for the first 6 hours. I’m between 100 and now 84…if i trend low i’ll shut off the pump. But so far it feels pretty good. Almost excited…and it’s only been 3 hours. LOL.
This entire thread is giving me a great deal of comfort. When I came to the pump almost a year ago, I fell so in love with the level of control it affords me that I began obsessing about what would happen if I ever have to give it up. The possibility that an injected basal could provide me with a flat line is very exciting and makes me fear the future a little bit less.
Ok so I am now running about -74% of my pump basal. So essentially 26 units of Tresiba this morning AND the first 6 hours of the day at 50% basal reduced on pump… now the last 3 hour 75% reduced pump basal. This drug has an 18 hour half life - so going cold turkey from pump to Tresiba - did not make sense from my doctor and I agree. Just took a 1/2 unit correction since I was creeping up to about 120. It is looking pretty good so far. Did lunch and breakfast with humalog injection - I think the next few days will be interesting.
I woke up this Morning at 57 - not a comfortable place to be, and a far cry from my usual 80. The difference from usual is that i skipped dinner entirely, and ate very little the rest of the day… i noticed in the past with levemir that my total daily calories the previous day does affect my fasting bs regardless if my blood sugar was perfect that day.
So i guess my basal is somehow covering more than basal… or maybe if i am more in metabolic ketosis then my basal needs drop. Will have to experiment with this.
I believe that our basal needs vary from day to day. I don’t think it’s a “set it and forget it” dose. I think even in the well-controlled diabetic, managing the dynamic moves in our metabolism is not simply fixing “mistakes” but a healthy response to the normal ebb and flow of our metabolism. I don’t think anyone taking exogenous insulin can ever completely separate the basal and bolus insulin. Mother nature is just so much better at this!
I use the 14-day standard day report using my CGM data to decide when to change insulin doses either up or down. Fourteen days is a nice duration to reveal trends versus a one or two day anomaly.
