I had to switch medications from janumet to jentadueto. 3 weeks later my blood sugar has gone through the roof. My doctor has given me Trulicity and frankly after reading all the side effects (negative) I’m scared to try it. I did fine on byetta and victoza. Does this mean I’ll do ok on Trulicity? New medications always make me anxious.
I think when we open up that new medication and we really read the information in that comes with it, it can appear that the medication is dangerous. But actually you need to take these warnings in context. These warnings are about cancer being observed in rats and the same things were found in other GLP-1 drugs like Byetta. In the millions and millions of doses of the GLP-1s that have been taken, they haven’t established a link to cancer in humans yet. All drugs have some side effects, heck, some people believe that the DPP-4 drugs (like your Janumet and JentaDueto) also cause cancer.
Despite all these warnings, the GLP-1 drugs like Trulicity are considered safe (and as safe as your previous medications) and you shouldn’t feel anxious about taking it.
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Hi, Tony! Great review of your experience with Trulicity. I have used it for~3 months after long term use of Victoza, then
weekly Bydureon. With V and B, I had awful heartburn/reflux and constipation which required prescription and OTC remedies. My A1c was much better, but…
With Trulicity I have been able to drop Rx acid meds and 4x/week laxatives and lose 10 lbs and hit a 5.7 A1c! Interesting note–the reason I changed was that my insurance would no longer pay for Bydureon, but would for Trulicity.
good to hear. just started trulicity this week. my numbers wer in the 400’s now did a reading and was cut in half to 200’s. I am hoping that over time trulicity will cause my numbers to go down to the 100’s to 200’s and even lower if I can accomplish that. so far so good no reactions to the injection so far .
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good to hear. I am hoping I can make the same amount of progress you have.
Greetings ALL~
this is my first post in the forum. I am a 65 years old man who was diagnosed with diabetes type II 25 years ago. Since then I am on medications for my diabetes. For the last 5 years I have been using Byetta 10 micro-gram twice a day along with Metformin 1000 mg twice a day, Glymberide 4 mg twice a day, and 45 units of Levimere long acting insulin at midnight. My HbA1c levels were 7-8 most of the time. Last week my diabetes doctor switched me to Trulicity1.5mg and I am supposed to start using it soon. But when I read the warnings about its side effects I felt very scared. I felt even more scared when I Googled the subject and read the scary comments by people who used Trulicity on the following link:
The comments on the article in the above link were all very negative and tell serious painful stories. Now, I am puzzled, what to do? Shall I go back to my doctor and tell him I am good with Byetta for the last 5 years and don’t want to take the risks associated with Trulicity or shall I switch as he prescribed to me. I have already the Trulicity injections (3 months supply) in my refrigerator now but scared to use them. I appreciate sharing your experience and advising me on this situation.
Mahmoud
Lawrence, Kansas.
I was given Trulicity today, and after reading all of the side effects it scares me to death. I want to loose weight, but the thiroid cancer risk concerning. I weight only 145, and a Type 1 diabetic. My Dr thought it would help with weight loss?
Where did you get this information. Did you read the prescribing information? Have you compared it with the prescribing information on anything else (like insulin?). Any drug can have adverse effects and there may be suspicions, but we need to take everything in context. Here are the adverse effects listed as having been found during the trials of Trulicity (found in the prescribing information).
- Nausea
- Diarrhea
- Vomiting
- Abdominal Pain
- Decreased Appetite
- Dyspepsia
- Fatigue
None of these is a serious side effect. Certainly modest compared to say Humalog (and this list doesn’t even pull out hypoglycemia which warrants an entire section of warning):
- Flu syndrome
- Pharyngitis
- Rhinitis
- Headache
- Pain
- Cough increased
- Infection
- Nausea
- Accidental injury
- Surgical procedure
- Fever
- Abdominal pain
- Asthenia
- Bronchitis
- Diarrhea
- Dysmenorrhea
- Myalgia
- Urinary tract infection
Now, let’s examine the Thyroid cancer concern. It was found to be associated with Thyroid cancer in rats. But this effect has not been found in humans at this point. And the FDA has required a monitoring program to look for this effect. So evidence that Trulicity causes thyroid cancer has not been found despite probably millions of patient years of Trulicity use. Think about it, if there hasn’t been any association found with this many millions of patient years then even if there was a problem it would be very, very rare. Despite that, the FDA erred on the side of caution and suggests that patients with a history of thyroid cancer should not use this drug.
It is important to keep things in context. Getting in your car and driving on the highway is likely to be orders of magnitude more dangerous than Trulicity. And your insulin is also more dangerous than Trulicity.
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I also started Trulicity this past week. I am taking .75 every Wednesday in the evening. The fist few days, I had no side effects at all. But today, Sunday, I have been nausious, stomach crps, and a or vomiting and water not diarhea. I was constapated since Wednesday. I was wondering how long this feeling lasted. What did you do to help get rid of the effects?? Any help would be appreciated[quote=“Tony_S, post:1, topic:46868, full:true”]
My doctor just started me on Trulicity this past week. I have been Type 2 for 13 years and have been unsuccessful at getting my A1c below 7.0. I had been taking a shot of Victoza in the a.m. and of Levemir just before bedtime. I also take oral meds Januvia and Metformin. I took my first Trulicity injection on Thursday and today woke up today (Saturday) with a headache but with a reading of 97 mg/dL. (Not really sure where the headache came from; side effect?) That’s one of my best a.m. readings. I know it’s too soon to retest for A1c improvement, so I was wondering if someone could share their Trulicity results with me. Taking the daily Victoza shot made me feel in control of my dosage, whereas a once-a-week shot seems, well, at least at the present time, mysterious. I mean: Is Trulicity really working and is it an improvement over daily Byetta or Victoza? Thanks in advance for sharing your experiences with this new drug treatment.
Tony
SF CA
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thats good to know. planning on going bback to trulicity as i had it for a 3 month test run. liked so far and going back to get a full prescription for 1 year from my endo.
I worked briefly for a group that did clinical trials on medications (mainly skin creams and such). Our subjects testing the medications were interviewed every week or two and given a long checklist of physical effects they noticed since the last interview. Please note: EVERY physical symptom had to be added to a list of possible side effects in research. Then, they get sifted and sorted by frequency and severity. Thus, if someone got nauseated during a clinical trial for sunscreen, it goes on the list. Heaven forbid, 10 people get kidney stones! Nobody would use it!
Side effects are possible, not guaranteed.
Margie,
What was your fasting insulin and C peptide?
How is evreyones carbohydrate intake with Trulicity? Does low carb give Hypos?