Type 2 - Started Afrezza Last Week

Metformin is free at most pharmacies. Why not just pick up a new bottle?

Is the Glooko that you are using the App for I-phone? I use the App and don't get the meal upper and lower limit lines although my graphs look similar. Did you select a certain setting or are you using the bluetooth device they sell? I also use a Relion Prime meter because the strips are cheap.

I used to recommend the Relions and used one back in the late '90s when my insurer wouldn't pay for strips, but the last two I've tested were reading very differently from my One Touch which I'd verified against a lab draw. My mini is the most accurate. The ultra, not so much.

I'll have to get me one of these Glookos and give it a whirl. I'm getting so few strips from Medicare it is hard to do any serious testing.

Pat,

It would be a good idea to keep glucose tablets, Smarties, and/or hard Sweetarts around to address hypos as sugary foods and juices are slower to hit the blood stream than pure glucose because they must be digested into glucose. Using more than you need is likely to cause a rebound high. And the fructose in the sugar won't do anything for your blood sugar, but it will go to your liver where it becomes liver fat. So using pure glucose is by far the best approach.

Depending on your weight, 2 g of glucose should raise you anywhere from 10 to 5 mg/dl within 15 minutes. The less you weigh the more effective the glucose. The 5 mg is for someone weighing in at 280 lbs.

I was looking at the clinical trials for Afrezza and there were a significant number of severe hypos reported, though of course, no explanation for the conditions surrounding them, but this suggests that they are possible. Until it is very clear what causes them, its always a good idea to have some glucose handy.

Also, since you are new to insulin, get into the habit of testing before you get into the car to drive. This should become a habit. It only takes one serious hypo while driving to kill someone, whether it be yourself or the people you hit.

I’ve had afrezza put me into the 60s a fair bit too but there doesn’t seem to be a whole lot of tendency to drive it much lower… And by the time I realize thete is any concern, it’s also time to realize there’s nothing to worry about because it’s a thing of the past. If I dosed 8u of novolog or humalog and was at 60 1 hour later I’d be very concerned and watching it like a hawk, with afrezza I just don’t even care

I’ve been using it for almost a week and have not required a single correction either up or down. At this rate my a1c will absolutely be in the 4s.

Sorry for the multiple replies I am without a proper computer here for a few day and relying on a smart phone. I have actually been seeing my basal requirements decrease (observing lower fasting levels) since starting afrezza too though, I’m trying not to read too much into that since there is no logical connection

Only connection would be increased insulin sensitivity, which is something Mann mentioned (IIRC) as an effect because of the lack of hyperinsulinemia that is present with fast-actings (i.e. the long tail).

That was (educated) speculation by Mann in my reading, so this is far from proven in any way.

Maybe Afrezza will serve to make the case...

Pat,

How’s it going? Any updates on how Afrezza is working (or not) for you? Did you adjust your I:C? Did it help? Any suggestions for other T2s thinking about Afrezza?