My doc prescribed U-500 insulin for me to start when I get my OmniPod in. He said I will need it because I use about 140 units per day. Does anyone else use U-500 with the OmniPod pump?

Wow, I didn’t even know the FDA had approved the Omnipod for use with U-500!

I do not use this, but I know that I’ve read about it on this site. Perhaps someone can find that discussion for you.

U-500 insulin posted 17 June 2009 by Abigail…http://www.tudiabetes.org/group/omnipodusers/forum/topics/u500-insulin

Steve, I’ve been using U-500 in my Pod since I started on the OmniPod last September. Absolutely no problem. In fact, there was a trial done about a year and a half ago using U-500 in the pods and they got some excellent results.

Thanks for the info. I was wondering how it was working in the OmniPod.

Bob, wondering if you’ve noticed any major differences with absorption/formulas etc with U-500, or is it the same, just a smaller ratio due to the concentration? Also, does U-500 cost more? Thanks!

Gina, U-500 is five times the strength of U-100, so we adjusted my carb to Insulin rate. The absorption rate is slower - it is not a fast acting insulin, so you have a little longer action to take into account. I have found that I have adjusted and don’t even think about it anymore. My cost through my prescription plan is identical for a 3 month supply to my old insulins (either pens or vials).

Got my Omnipod starter kit on Friday. Making an appointment with the doctor for training next week. Already have one vile of U-500.

Good luck with the pod. I have loved mine. Most days I have to think about it being on.

Thanks for the info!!

How’s it going with the U-500? Are you still using it? My doc just faxed in the perscription so I hope to have the U-500 insulin next week.



No. I am using novalog now. The U500 caused me to be put in the hospital twice for extreme lows. Be careful.