Moderna Vaccine higher blood sugar

Actually my bg post Pfizer shot was a higher for the next few days. I thought it was due to my diet including post shot celebratory pretzels.
Even though I bolused for the pretzels, it was much higher than expected. I will watch it next shot.

I am scheduled for my first shot this afternoon. I will follow my BG history and insulin usage on my 670G/guardian system and report back.

I got my first Moderna shot Friday 2/26 at 12:30 pm and it has been a pretty wild ride so far. Didnā€™t feel the shot or any pain, but although I am OMAD low carb diet, I still normally need to take an additional 4 units of fast acting Humalog a couple of hours after meal and then another 2.6 units two hours later to stay flatlined.

I only took one of my 2 afternoon doses as my BG, instead of flatlining as normal in the 85-90 range, it tanked to 40 mg/dl. I ate a few dried plums and a few small pieces of chocolate but was having a real hard time getting BG up and maintaining over 65 which is the lowest I am comfortable at. This continued until 1 AM and then it was like a switch got flipped.

My BG shot up to 195 and just would not come down. This was more persistent than Thanksgiving or Christmas dinner with my grand daughters stuffing me with their latest sweet treats and ice cream. My temperature quickly rose about 3 degrees and by 11 AM Saturday morning my arm was quite sore at the injection site as well. I can normally flatline with a BG below 95 with 18-25 daily units of fast acting Humalog, but when I checked my digital pen, it was showing that I had taken a total of 78.6 units for the past 24 hours and my BG would not go below 180.

Suddenly at 2 AM on Sunday morning, my fever vanished and my BG plummeted from 180 to 91 over about a 45 minute period. Since 2 AM on Sunday, I have been totally fine except for mild discomfort at the injection site.

Maybe, I am just a big pain baby, but this being my first dose with this kind of reaction, I will reside within a couple of miles from a major hospital in Boston when I get my second dose on the 26th of March.

One interesting note, is that these kinds of experiences anecdotally do seem to occur in individuals that have had even a mild case of Covid. In my case, however, there have not been any known cases at work, I live countryside where there have only been a handful of cases in total, and I have undergone several PCR Covid tests over the past few weeks which all tested negative so I donā€™t think that I have had any Covid.

I, too, received my first Moderna vaccine on February 26. I did have a low level of pain and swelling at the site but otherwise itā€™s been uneventful.

After reading comments in this thread, I decided to look more closely at the statistics for the last three days and compare them to the statistics for the previous three-day period.

My average blood glucose did go up in the last three days from 99 mg/dL to 107 mg/dL. My time in range increased to 86% from 85% in the three days before the shot. My standard deviation improved from 22 mg/dL for the three days before the injection to 19 mg/dL for the last three days.

So the only anomaly is the average BG increase but I experience slow rolling changes like that from time to time. I make regular changes to basal rates and insulin sensitivity (ISF aka correction factor) settings as my diabetes is not a stable target. So this could be from the Covid vaccination or it could be just the normal lower frequency excursions that I often experience.

My average total daily dose of insulin (TDD) for the last three days measured 31.5 units/day plus an average of one 4-unit cartridge of Afrezza for both three-day periods.

I donā€™t think the Moderna vaccination affected my glucose metabolism; if it did, the effect was minimal.

Really? Maybe Feb 26?

@MM1 Thanks for pointing out this error. It was on February 26; March 26 is my scheduled second dose. I corrected my comment. Congrats on getting your vaccination scheduled!

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I really appreciate all those who posted their experiences with the vaccine. I must admit, I am very skiddish about taking it. I have control which can only be described as precarious at best. My A1C is 5.7 which looks good on the surface but is the result of hyper vigilance. Even at that, yesterday I hit a surprise 40(even though Dex alarmed me at 65 and I treated). Sigh. With the swings that some are posting Iā€™m just plain afraid that with my hypo unawareness on one hand and throwing ketones at 190 that I wouldnā€™t survive the treatment. Advice is welcome. Thank you.

@yeagan
From what I am reading, everyone is reacting differently (and perhaps, not at all). Yes, it is one more variable to consider, but I got a vaccine for multiple reasons. The biggest reason is that I wanted some freedom to be out in the world again. When covid first hit I became hyper-vigilant about doing what I could to not catch covid because I didnā€™t want to end up hospitalized and unable to make my own diabetes decisions. For me, the vaccine is a huge step to freedom.

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Thank you for replying. Iā€™m glad you are doing well.

@CJ114 your reaction to the first shot makes me wonder if you have previously had a COVID infection and didnā€™t know it, because people with prior COVID infections tend to a have a reaction to the first shot more similar to most peopleā€™s reactions to the second shot. I believe if you had a prior infection, they are now saying you do not need a second shot, but if you donā€™t know, I can imagine youā€™d still want it.

On February 16th both T1 and T2 became eligible in New York. Iā€™m T1 and also have asthma which was also included in the list.

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How is your blood sugar when you donā€™t eat? Like when you must fast for a blood draw or a medical procedure?

Many people find that fasting stabilizes their glucose and reduces variability. This assumes, of course, that your basal insulin is balanced nicely.

If fasting also stabilizes your glucose, you could plan a fasting day on the day you receive the vaccine.

I also have A1cs in the 5s and I tend to have too many lows even using a CGM. I got the first shot of Pfizer on 2/25 and had no reaction. Many people are saying the second dose shows more side effects but Iā€™m really not worried. Having the pump + CGM does give me peace of mind about dealing with sudden changes.

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Good grief, your experience sounds really scary! I had nothing but a sore arm, but am worried about the second Moderna shot. You had quite a time with a temperature and all the extra insulin you needed. So glad that you got through that ok. I think that you are very wise to be very close to an ER for your second dose. At least you will be more prepared for a reaction if you have one, which hopefully you wonā€™t.

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Thank you,Terry4 for your reply. I recently had to fast for a colonoscopy and I did fine. My bg stayed pretty stable so my basals are okay or close. I do have variability like everyone does I guess. If and when I get the vaccine I will keep that in mind about fasting. It is just hard to decifer the truth from so many variables. That is why I turned to this site. Thank you.

I also have a pump and cgm. The 40 fiasco was during the first 24 hours with a new sensor but I didnā€™t really feel any symptoms. Thank goodness dex alarmed me when it thought I was 65 but was 40. Thank you for your reply.

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2nd dose update . Got Modrna second jab on Saturday. Fever, BG went to 300, chills, nausea, headache. It was awful. Had to bolus all day to cover highs and cover Ginger brew , which was the only think to get rid of the nausea. Could not eat. Alternated Tylenols and advil for fever and pain. Usually take 15 units total/day. 25 units for 2 days post vaccine. Back to human status 2.5 days later.
Good luck everyone!

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How long after the vaccine did it take to feel ill? So happy that you are feeling better!

8 hours

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